1.
J Org Chem
; 79(17): 7935-44, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25078565
RESUMO
A series of novel polyfunctionalized pyrido[2,3-b]indoles were synthesized by three- or four-component domino reactions under microwave irradiation. This protocol has the advantages of readily available starting materials, short reaction times, high yields, easy workup, and high chemo- and regioselectivities.
2.
ACS Comb Sci
; 17(1): 24-31, 2015 Jan 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25412896
RESUMO
An efficient synthesis of novel functionalized 1,8-naphthyridine and chromeno[2,3-b]quinoline derivatives via cascade reaction of 2-chloroquinoline-3-carbaldehyde and enaminones or cyclic 1,3-dicarbonyl compounds was developed. All of the 1,8-naphthyridine derivatives synthesized were evaluated for their antiproliferative properties in vitro against cancer cells and several compounds were found to have high activities.