Detalhe da pesquisa
1.
Secreted Amyloid Precursor Protein Alpha (sAPPα) Regulates the Cellular Proteome and Secretome of Mouse Primary Astrocytes.
Int J Mol Sci
; 24(8)2023 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108327
2.
An altered secretome is an early marker of the pathogenesis of CLN6 Batten disease.
J Neurochem
; 157(3): 764-780, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33368303
3.
Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.
Mol Ther
; 27(10): 1836-1847, 2019 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31331814
4.
Longitudinal In Vivo Monitoring of the CNS Demonstrates the Efficacy of Gene Therapy in a Sheep Model of CLN5 Batten Disease.
Mol Ther
; 26(10): 2366-2378, 2018 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30078766
5.
Characterisation of early changes in ovine CLN5 and CLN6 Batten disease neural cultures for the rapid screening of therapeutics.
Neurobiol Dis
; 100: 62-74, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28065762
6.
Patterned, but not tonic, optogenetic stimulation in motor thalamus improves reaching in acute drug-induced Parkinsonian rats.
J Neurosci
; 35(3): 1211-6, 2015 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25609635
7.
Experimental therapies in the neuronal ceroid lipofuscinoses.
Biochim Biophys Acta
; 1852(10 Pt B): 2292-300, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957554
8.
Recent studies of ovine neuronal ceroid lipofuscinoses from BARN, the Batten Animal Research Network.
Biochim Biophys Acta
; 1852(10 Pt B): 2279-86, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26073432
9.
Viral vector-based tools advance knowledge of basal ganglia anatomy and physiology.
J Neurophysiol
; 115(4): 2124-46, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26888111
10.
Expression of the developmental transcription factor Fezf2 identifies a distinct subpopulation of layer 5 intratelencephalic-projection neurons in mature mouse motor cortex.
J Neurosci
; 34(12): 4303-8, 2014 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24647950
11.
Inhibition of storage pathology in prenatal CLN5-deficient sheep neural cultures by lentiviral gene therapy.
Neurobiol Dis
; 62: 543-50, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24269732
12.
Neuroproteomic Analysis after SARS-CoV-2 Infection Reveals Overrepresented Neurodegeneration Pathways and Disrupted Metabolic Pathways.
Biomolecules
; 13(11)2023 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38002279
13.
Effect of soluble amyloid precursor protein-alpha on adult hippocampal neurogenesis in a mouse model of Alzheimer's disease.
Mol Brain
; 15(1): 5, 2022 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34980189
14.
Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures.
Sci Rep
; 12(1): 11286, 2022 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35789177
15.
Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer's disease.
Acta Neuropathol Commun
; 10(1): 38, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331340
16.
Neural development in human embryonic stem cells-applications of lentiviral vectors.
J Cell Biochem
; 112(8): 1955-62, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21445864
17.
Deficiency of the Lysosomal Protein CLN5 Alters Lysosomal Function and Movement.
Biomolecules
; 11(10)2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34680045
18.
A schizophrenia risk factor induces marked anatomical deficits at GABAergic-dopaminergic synapses in the rat ventral tegmental area: Essential evidence for new targeted therapies.
J Comp Neurol
; 529(18): 3946-3973, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34338311
19.
Lentivirus-Mediated Expression of Human Secreted Amyloid Precursor Protein-Alpha Promotes Long-Term Induction of Neuroprotective Genes and Pathways in a Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
; 79(3): 1075-1090, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33386801
20.
CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain.
Mol Ther Methods Clin Dev
; 19: 447-458, 2020 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33294493