Detalhe da pesquisa
1.
A comparative analysis of recombinant Fab and full-length antibody production in Chinese hamster ovary cells.
Biotechnol Bioeng
; 118(12): 4815-4828, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34585737
2.
Escherichia coli "TatExpress" strains export several g/L human growth hormone to the periplasm by the Tat pathway.
Biotechnol Bioeng
; 116(12): 3282-3291, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31429928
3.
Mitochondrial aconitase is a key regulator of energy production for growth and protein expression in Chinese hamster ovary cells.
Metabolomics
; 14(10): 136, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830403
4.
IgG light chain-independent secretion of heavy chain dimers: consequence for therapeutic antibody production and design.
Biochem J
; 474(18): 3179-3188, 2017 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28784690
5.
Molecular Insights into the Thermal Stability of mAbs with Variable-Temperature Ion-Mobility Mass Spectrometry.
Chembiochem
; 17(1): 46-51, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26534882
6.
Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fcγ receptors and functional impact on immune cells in vitro.
MAbs
; 16(1): 2300155, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38241085
7.
Engineering an improved IgG4 molecule with reduced disulfide bond heterogeneity and increased Fab domain thermal stability.
J Biol Chem
; 287(29): 24525-33, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22610095
8.
TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life.
MAbs
; 15(1): 2160229, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36788124
9.
Antibodies as drugs-a Keystone Symposia report.
Ann N Y Acad Sci
; 1519(1): 153-166, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36382536
10.
The phage abortive infection system, ToxIN, functions as a protein-RNA toxin-antitoxin pair.
Proc Natl Acad Sci U S A
; 106(3): 894-9, 2009 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19124776
11.
On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.
Commun Biol
; 4(1): 1031, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475514
12.
Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.
Front Immunol
; 10: 390, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30899264
13.
Relative Contribution of Framework and CDR Regions in Antibody Variable Domains to Multimerisation of Fv- and scFv-Containing Bispecific Antibodies.
Antibodies (Basel)
; 7(3)2018 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31544885
14.
Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions.
Commun Biol
; 1: 146, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30272022
15.
Alternative antibody Fab' fragment PEGylation strategies: combination of strong reducing agents, disruption of the interchain disulphide bond and disulphide engineering.
Protein Eng Des Sel
; 20(5): 227-34, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17452434
16.
Development of a high yielding E. coli periplasmic expression system for the production of humanized Fab' fragments.
Biotechnol Prog
; 33(1): 212-220, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27790865
17.
High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection.
Clin Exp Gastroenterol
; 10: 169-175, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28765714
18.
Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life.
MAbs
; 8(7): 1336-1346, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27315033
19.
Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding.
MAbs
; 8(7): 1319-1335, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27532598
20.
Production of antibodies and antibody fragments in Escherichia coli and a comparison of their functions, uses and modification.
Curr Opin Drug Discov Devel
; 6(2): 188-96, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12669454