Detalhe da pesquisa
1.
Long-read sequencing for fast and robust identification of correct genome-edited alleles: PCR-based and Cas9 capture methods.
PLoS Genet
; 20(3): e1011187, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38457464
2.
Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6.
Neurobiol Dis
; 190: 106363, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37996040
3.
Modulation of Aß42 Aggregation Kinetics and Pathway by Low-Molecular-Weight Inhibitors.
Chembiochem
; 24(7): e202200760, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652672
4.
Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.
Angew Chem Int Ed Engl
; 61(46): e202205858, 2022 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36115062
5.
Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants.
BMC Biol
; 16(1): 70, 2018 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925374
6.
Analysing the outcome of CRISPR-aided genome editing in embryos: Screening, genotyping and quality control.
Methods
; 121-122: 68-76, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28363792
7.
Structure of Staphylococcus aureus adenylosuccinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery.
Acta Crystallogr D Biol Crystallogr
; 66(Pt 8): 881-8, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20693687
8.
Structural rearrangement of amyloid-ß upon inhibitor binding suppresses formation of Alzheimer's disease related oligomers.
Elife
; 92020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33095161
9.
The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities.
PLoS One
; 15(6): e0230162, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542000
10.
Structural characterization of the intrinsically disordered domain of Mycobacterium tuberculosis protein tyrosine kinase A.
FEBS Lett
; 592(7): 1233-1245, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29494752
11.
Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair.
Genome Med
; 8(1): 16, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26876963
12.
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.
Nat Commun
; 7: 12444, 2016 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27534441