Detalhe da pesquisa
1.
Presenilin: A Multi-Functional Molecule in the Pathogenesis of Alzheimer's Disease and Other Neurodegenerative Diseases.
Int J Mol Sci
; 25(3)2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38339035
2.
Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
J Neurosci
; 42(8): 1574-1586, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34987110
3.
Apolipoprotein E4 inhibits γ-secretase activity via binding to the γ-secretase complex.
J Neurochem
; 164(6): 858-874, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36582176
4.
High temperature promotes amyloid ß-protein production and γ-secretase complex formation via Hsp90.
J Biol Chem
; 295(52): 18010-18022, 2020 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067321
5.
Presenilin 1 deficiency impairs Aß42-to-Aß40- and angiotensin-converting activities of ACE.
Front Aging Neurosci
; 15: 1098034, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36875692
6.
Aß42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood-brain barrier model.
Mol Brain
; 16(1): 15, 2023 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36698209
7.
Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts.
Front Aging Neurosci
; 14: 902525, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35783133