Detalhe da pesquisa
1.
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models.
Cell
; 142(3): 387-97, 2010 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20655099
2.
Rapid initiation of cell cycle reentry processes protects neurons from amyloid-ß toxicity.
Proc Natl Acad Sci U S A
; 118(12)2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737393
3.
ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.
Hum Mol Genet
; 30(11): 971-984, 2021 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33729478
4.
Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy.
Neuropathol Appl Neurobiol
; 49(4): e12931, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37565253
5.
TDP-43 pathology and functional deficits in wild-type and ALS/FTD mutant cyclin F mouse models.
Neuropathol Appl Neurobiol
; 49(2): e12902, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36951214
6.
Cell-specific MAPT gene expression is preserved in neuronal and glial tau cytopathologies in progressive supranuclear palsy.
Acta Neuropathol
; 146(3): 395-414, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37354322
7.
Distribution Patterns of Astrocyte Populations in the Human Cortex.
Neurochem Res
; 48(4): 1222-1232, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35930103
8.
Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis.
Brain
; 145(5): 1598-1609, 2022 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35202463
9.
Peptides for trans-blood-brain barrier delivery.
J Labelled Comp Radiopharm
; 66(9): 237-248, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37002811
10.
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
Acta Neuropathol
; 144(4): 637-650, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35780436
11.
Developmental delay and late onset HBSL pathology in hypomorphic Dars1M256L mice.
Neurochem Res
; 47(7): 1972-1984, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35357600
12.
Syntaxins 6 and 8 facilitate tau into secretory pathways.
Biochem J
; 478(7): 1471-1484, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33769438
13.
Understanding In Vitro Pathways to Drug Discovery for TDP-43 Proteinopathies.
Int J Mol Sci
; 23(23)2022 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499097
14.
Interaction between the guanylate kinase domain of PSD-95 and the proline-rich region and microtubule binding repeats 2 and 3 of tau.
Biochem Cell Biol
; 99(5): 606-616, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33794133
15.
Neurodegeneration and Motor Deficits in the Absence of Astrogliosis upon Transgenic Mutant TDP-43 Expression in Mature Mice.
Am J Pathol
; 190(8): 1713-1722, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32371051
16.
Onset of hippocampal network aberration and memory deficits in P301S tau mice are associated with an early gene signature.
Brain
; 143(6): 1889-1904, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375177
17.
TDP-43 and Inflammation: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Int J Mol Sci
; 22(15)2021 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34360544
18.
Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.
J Neurosci
; 39(48): 9645-9659, 2019 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31641049
19.
CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation.
J Biol Chem
; 294(38): 14149-14162, 2019 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31366728
20.
Reduction of advanced tau-mediated memory deficits by the MAP kinase p38γ.
Acta Neuropathol
; 140(3): 279-294, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32725265