Detalhe da pesquisa
1.
Salazinic Acid and Norlobaridone from the Lichen Hypotrachyna cirrhata: Antioxidant Activity, α-Glucosidase Inhibitory and Molecular Docking Studies.
Molecules
; 28(23)2023 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38067568
2.
Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases.
Molecules
; 27(19)2022 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36234686
3.
In vivo anti-inflammatory activity and docking study of newly synthesized benzimidazole derivatives bearing oxadiazole and morpholine rings.
Bioorg Chem
; 70: 107-117, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27923497
4.
Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus E protein inhibitors.
Bioorg Med Chem Lett
; 25(8): 1747-1752, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25791449
5.
Mechanism of immunoprotective effects of curcumin in DLM-induced thymic apoptosis and altered immune function: an in silico and in vitro study.
Immunopharmacol Immunotoxicol
; 37(6): 488-98, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26471321
6.
Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8.
Bioorg Chem
; 57: 116-120, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25462986
7.
Thiazolotriazoles As Anti-infectives: Design, Synthesis, Biological Evaluation and In Silico Studies.
ACS Omega
; 9(8): 8846-8861, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38434818
8.
Scaffold identification and drug repurposing for finding potential Dengue envelope inhibitors through ligand-based pharmacophore model.
J Biomol Struct Dyn
; 41(21): 11916-11929, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36709443
9.
Synthetic and Medicinal Chemistry Approaches Toward WEE1 Kinase Inhibitors and Its Degraders.
ACS Omega
; 8(23): 20196-20233, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37323408
10.
AMPK targets a proto-oncogene TPD52 (isoform 3) expression and its interaction with LKB1 suppress AMPK-GSK3ß signaling axis in prostate cancer.
J Cell Commun Signal
; 17(3): 957-974, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37040029
11.
Synthesis of novel thiazoles bearing lupeol derivatives as potent anticancer and anti-inflammatory agents.
Nat Prod Res
; : 1-8, 2023 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36691946
12.
Synthesis of aminomethyl linked (+)-usnic acid derivatives via the Mannich reaction and evaluation of their biological activities.
Nat Prod Res
; : 1-7, 2023 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37812197
13.
Development of 2-chloroquinoline based heterocyclic frameworks as dual inhibitors of SARS-CoV-2 MPro and PLPro.
Int J Biol Macromol
; 242(Pt 2): 124772, 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37172706
14.
Continuous flow process for preparing budesonide.
J Flow Chem
; 12(2): 237-246, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35465101
15.
Machine Learning in Drug Discovery: A Review.
Artif Intell Rev
; 55(3): 1947-1999, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34393317
16.
Design, synthesis and cytotoxic activity studies of alkyne linked analogues of Nimbolide.
Fitoterapia
; 161: 105246, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35760229
17.
A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Eur J Med Chem
; 212: 113149, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33445154
18.
Structure-based discovery of small molecule APC-Asef interaction inhibitors: In silico approaches and molecular dynamics simulations.
J Mol Model
; 26(8): 207, 2020 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32676810
19.
Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy.
Eur J Med Chem
; 165: 115-132, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30665142
20.
A review on HCV inhibitors: Significance of non-structural polyproteins.
Eur J Med Chem
; 164: 576-601, 2019 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639895