1.
J Am Chem Soc
; 127(8): 2396-7, 2005 Mar 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15724986
RESUMO
A peptide-cleaving catalyst selective for peptide deformylase (PDF) was obtained from a library containing about 15 000 catalyst candidates. The catalyst cleaved the polypeptide backbone of PDF at Gln(152)-Arg(153). Docking simulations suggested multiple modes of interactions in the complex formed between the catalyst and PDF.