Detalhe da pesquisa
1.
A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane.
Cell Mol Life Sci
; 81(1): 98, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38386110
2.
Chemoenzymatic Production of Enantiocomplementary 2-Substituted 3-Hydroxycarboxylic Acids from L-α-Amino Acids.
Adv Synth Catal
; 363(11): 2866-2876, 2021 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34276272
3.
Biocatalytic Construction of Quaternary Centers by Aldol Addition of 3,3-Disubstituted 2-Oxoacid Derivatives to Aldehydes.
J Am Chem Soc
; 142(46): 19754-19762, 2020 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33147013
4.
Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes.
Adv Synth Catal
; 361(11): 2673-2687, 2019 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31680790
5.
Nucleophile Promiscuity of Engineered Classâ II Pyruvate Aldolase YfaU from E.â Coli.
Angew Chem Int Ed Engl
; 57(14): 3583-3587, 2018 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29363239
6.
Intramolecular Benzoin Reaction Catalyzed by Benzaldehyde Lyase from Pseudomonas Fluorescens Biovar I.
Angew Chem Int Ed Engl
; 56(19): 5304-5307, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28387004
7.
Untargeted metabolomics in doping control: detection of new markers of testosterone misuse by ultrahigh performance liquid chromatography coupled to high-resolution mass spectrometry.
Anal Chem
; 87(16): 8373-80, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26200763
8.
Expedient synthesis of C-aryl carbohydrates by consecutive biocatalytic benzoin and aldol reactions.
Chemistry
; 21(8): 3335-46, 2015 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25640727
9.
Engineered L-serine hydroxymethyltransferase from Streptococcus thermophilus for the synthesis of α,α-dialkyl-α-amino acids.
Angew Chem Int Ed Engl
; 54(10): 3013-7, 2015 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25611820
10.
Engineering the donor selectivity of D-fructose-6-phosphate aldolase for biocatalytic asymmetric cross-aldol additions of glycolaldehyde.
Chemistry
; 20(39): 12572-83, 2014 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25146467
11.
Casuarine stereoisomers from achiral substrates: chemoenzymatic synthesis and inhibitory properties.
J Org Chem
; 79(11): 5386-9, 2014 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24810734
12.
Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats.
Pharmacol Res
; 77: 47-56, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24044986
13.
Chemo-enzymatic synthesis and glycosidase inhibitory properties of DAB and LAB derivatives.
Org Biomol Chem
; 11(12): 2005-21, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23381224
14.
Biocatalytic Synthesis of Homochiral 2-Hydroxy-4-butyrolactone Derivatives by Tandem Aldol Addition and Carbonyl Reduction.
ACS Catal
; 13(8): 5348-5357, 2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37123603
15.
Chemoenzymatic synthesis, structural study and biological activity of novel indolizidine and quinolizidine iminocyclitols.
Org Biomol Chem
; 10(31): 6309-21, 2012 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22735612
16.
Highly efficient aldol additions of DHA and DHAP to N-Cbz-amino aldehydes catalyzed by L-rhamnulose-1-phosphate and L-fuculose-1-phosphate aldolases in aqueous borate buffer.
Org Biomol Chem
; 9(24): 8430-6, 2011 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22042499
17.
Synthesis of γ-Hydroxy-α-amino Acid Derivatives by Enzymatic Tandem Aldol Addition-Transamination Reactions.
ACS Catal
; 11(8): 4660-4669, 2021 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34603828
18.
Antioxidant activities of hydroxytyrosol main metabolites do not contribute to beneficial health effects after olive oil ingestion.
Drug Metab Dispos
; 38(9): 1417-21, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20516254
19.
Structure-guided minimalist redesign of the L-fuculose-1-phosphate aldolase active site: expedient synthesis of novel polyhydroxylated pyrrolizidines and their inhibitory properties against glycosidases and intestinal disaccharidases.
Chemistry
; 16(35): 10691-706, 2010 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20661960
20.
Cytotoxicity and enzymatic activity inhibition in cell lines treated with novel iminosugar derivatives.
Glycoconj J
; 27(2): 277-85, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20041292