Detalhe da pesquisa
1.
Short-term toxicogenomics as an alternative approach to chronic in vivo studies for derivation of points of departure: A case study in the rat with a triazole fungicide.
Regul Toxicol Pharmacol
; 113: 104655, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32268158
2.
Systematic reviews and meta-analyses of human and animal evidence of prenatal diethylhexyl phthalate exposure and changes in male anogenital distance.
J Toxicol Environ Health B Crit Rev
; 21(4): 207-226, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30199328
3.
Polybrominated diphenyl ether (PBDE) neurotoxicity: a systematic review and meta-analysis of animal evidence.
J Toxicol Environ Health B Crit Rev
; 21(4): 269-289, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30352012
4.
Comparative response of rat and rabbit conceptuses in vitro to inhibitors of histiotrophic nutrition.
Birth Defects Res B Dev Reprod Toxicol
; 104(1): 1-10, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25652268
5.
Transcriptomic point of departure determination: a comparison of distribution-based and gene set-based approaches.
Front Genet
; 15: 1374791, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38784034
6.
From Pipeline to Plant Protection Products: Using New Approach Methodologies (NAMs) in Agrochemical Safety Assessment.
J Agric Food Chem
; 72(19): 10710-10724, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38688008
7.
Development of a human liver microphysiological coculture system for higher throughput chemical safety assessment.
Toxicol Sci
; 199(2): 227-245, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38335931
8.
Transcriptome analysis of the dihydrotestosterone-exposed fetal rat gubernaculum identifies common androgen and insulin-like 3 targets.
Biol Reprod
; 89(6): 143, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24174575
9.
A microRNA or messenger RNA point of departure estimates an apical endpoint point of departure in a rat developmental toxicity model.
Birth Defects Res
; 114(11): 559-576, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35596682
10.
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.
Toxicol Sci
; 190(2): 127-132, 2022 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36165699
11.
Uncovering gene regulatory networks during mouse fetal germ cell development.
Biol Reprod
; 84(4): 790-800, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21148109
12.
A rat subchronic study transcriptional point of departure estimates a carcinogenicity study apical point of departure.
Food Chem Toxicol
; 147: 111869, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217531
13.
Insulin-like 3 exposure of the fetal rat gubernaculum modulates expression of genes involved in neural pathways.
Biol Reprod
; 83(5): 774-82, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20631401
14.
A Rat Liver Transcriptomic Point of Departure Predicts a Prospective Liver or Non-liver Apical Point of Departure.
Toxicol Sci
; 176(1): 86-102, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32384157
15.
Dioxin male rat reproductive toxicity mode of action and relative potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran characterized by fetal pituitary and testis transcriptome profiling.
Reprod Toxicol
; 93: 146-162, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32109520
16.
Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone.
Toxicol Sci
; 97(2): 491-503, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17361019
17.
Mono-(2-ethylhexyl) phthalate rapidly increases celsr2 protein phosphorylation in HeLa cells via protein kinase C and casein kinase 1.
Toxicol Sci
; 91(1): 255-64, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16484285
18.
Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages.
Toxicol Sci
; 93(2): 369-81, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16809437
19.
Hybrid GPCR/cadherin (Celsr) proteins in rat testis are expressed with cell type specificity and exhibit differential Sertoli cell-germ cell adhesion activity.
J Androl
; 26(4): 529-38, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15955893
20.
Defining the cellular and molecular mechanisms of toxicant action in the testis.
Toxicol Lett
; 135(3): 167-83, 2002 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12270675