Detalhe da pesquisa
1.
Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects.
J Chem Inf Model
; 60(11): 5457-5474, 2020 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32813975
2.
Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies.
Bioorg Med Chem Lett
; 29(23): 126717, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31635932
3.
Optimization of the Central Core of Indolinone-Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists.
ACS Med Chem Lett
; 2(8): 644-9, 2011 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900359
4.
Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids.
ACS Med Chem Lett
; 2(12): 938-42, 2011 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900284
5.
Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
J Med Chem
; 54(20): 7299-317, 2011 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21916510
6.
Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway.
EMBO Mol Med
; 2(12): 504-15, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21064192
7.
Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits.
Mol Cell Biol
; 29(6): 1538-53, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19139271
8.
GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
J Biol Chem
; 284(17): 11385-95, 2009 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19233845
9.
Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists.
Bioorg Med Chem Lett
; 17(7): 2080-5, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17321742