1.
Org Biomol Chem
; 17(13): 3319-3323, 2019 03 27.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30869722
RESUMO
Electrochemical oxidative radical trifluoromethylation/semipinacol rearrangement sequences of alkenyl alcohols were developed in this study. This approach is environmentally benign and uses the shelf-stable Langlois reagent as a trifluoromethyl radical precursor and electrons as the oxidizing reagents. The present protocol offers a facile route to prepare ß-trifluoromethylated ketone derivatives.