Detalhe da pesquisa
1.
Biallelic CACNA2D1 loss-of-function variants cause early-onset developmental epileptic encephalopathy.
Brain
; 145(8): 2721-2729, 2022 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35293990
2.
Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits.
Proc Natl Acad Sci U S A
; 111(24): 8979-84, 2014 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24889613
3.
The inhibition of functional expression of calcium channels by prion protein demonstrates competition with α2δ for GPI-anchoring pathways.
Biochem J
; 458(2): 365-74, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24329154
4.
Calcium currents are enhanced by α2δ-1 lacking its membrane anchor.
J Biol Chem
; 287(40): 33554-66, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22869375
5.
The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function.
Proc Natl Acad Sci U S A
; 107(4): 1654-9, 2010 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080692
6.
ADAM17 Mediates Proteolytic Maturation of Voltage-Gated Calcium Channel Auxiliary α2δ Subunits, and Enables Calcium Current Enhancement.
Function (Oxf)
; 3(3): zqac013, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35462614
7.
The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin.
J Neurosci
; 29(13): 4076-88, 2009 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19339603
8.
A single conserved proline residue determines the membrane topology of stomatin.
Biochem J
; 418(3): 587-94, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19032151
9.
Fight or flight: The culprit is lurking in the neighbourhood.
Cell Calcium
; 87: 102180, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065986
10.
Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b.
Biochem J
; 412(3): 469-75, 2008 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18307415
11.
Disruption of the Key Ca2+ Binding Site in the Selectivity Filter of Neuronal Voltage-Gated Calcium Channels Inhibits Channel Trafficking.
Cell Rep
; 29(1): 22-33.e5, 2019 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31577951
12.
Proteolytic maturation of α2δ controls the probability of synaptic vesicular release.
Elife
; 72018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29916807
13.
The α2δ-like Protein Cachd1 Increases N-type Calcium Currents and Cell Surface Expression and Competes with α2δ-1.
Cell Rep
; 25(6): 1610-1621.e5, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30404013
14.
LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit.
Sci Rep
; 7: 43802, 2017 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28256585
15.
Strong modulation by RFamide neuropeptides of the ASIC1b/3 heteromer in competition with extracellular calcium.
Neuropharmacology
; 50(8): 964-74, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16549075
16.
Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed.
Sci Rep
; 6: 24531, 2016 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27076051
17.
Proteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.
Elife
; 52016 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27782881
18.
Presynaptic HCN1 channels regulate Cav3.2 activity and neurotransmission at select cortical synapses.
Nat Neurosci
; 14(4): 478-86, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21358644
19.
A new look at calcium channel α2δ subunits.
Curr Opin Neurobiol
; 20(5): 563-71, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20579869
20.
Zebrafish acid-sensing ion channel (ASIC) 4, characterization of homo- and heteromeric channels, and identification of regions important for activation by H+.
J Biol Chem
; 282(42): 30406-13, 2007 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17686779