Detalhe da pesquisa
1.
Metabolites as regulators of insulin sensitivity and metabolism.
Nat Rev Mol Cell Biol
; 19(10): 654-672, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30104701
2.
Leptin and insulin act on POMC neurons to promote the browning of white fat.
Cell
; 160(1-2): 88-104, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25594176
3.
Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.
Cell
; 159(2): 318-32, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25303528
4.
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids.
Nature
; 606(7916): 968-975, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35676490
5.
Editorial Expression of Concern: Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase.
Nature
; 629(8013): E15, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710933
6.
PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53.
Proc Natl Acad Sci U S A
; 119(47): e2206923119, 2022 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375063
7.
Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4.
Proc Natl Acad Sci U S A
; 117(49): 31309-31318, 2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33214151
8.
Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs).
J Lipid Res
; 62: 100108, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34418413
9.
Adipocyte Regulation of Insulin Sensitivity and the Risk of Type 2 Diabetes.
N Engl J Med
; 388(22): 2071-2085, 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37256977
10.
RBP4 increases lipolysis in human adipocytes and is associated with increased lipolysis and hepatic insulin resistance in obese women.
FASEB J
; 34(5): 6099-6110, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32167208
11.
AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1.
Mol Cell
; 49(6): 1167-75, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23453806
12.
Insulin Resistance Is Not Sustained Following Denervation in Glycolytic Skeletal Muscle.
Int J Mol Sci
; 22(9)2021 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34066429
13.
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Nature
; 508(7495): 258-62, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24717514
14.
Discovery of FAHFA-Containing Triacylglycerols and Their Metabolic Regulation.
J Am Chem Soc
; 141(22): 8798-8806, 2019 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31056915
15.
Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements.
Anal Chem
; 90(8): 5358-5365, 2018 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29578702
16.
AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs.
Nat Chem Biol
; 12(5): 367-372, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27018888
17.
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
Nature
; 484(7394): 333-8, 2012 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22466288
18.
PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells.
J Biol Chem
; 291(11): 5664-5675, 2016 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26797128
19.
Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses.
J Biol Chem
; 291(42): 22207-22217, 2016 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27573241
20.
Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation.
J Am Chem Soc
; 139(13): 4943-4947, 2017 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28350171