Detalhe da pesquisa
1.
Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV.
J Hepatol
; 74(5): 1075-1086, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33333207
2.
Predictability of human pharmacokinetics of drugs that undergo hepatic organic anion transporting polypeptide (OATP)-mediated transport using single-species allometric scaling in chimeric mice with humanized liver: integration with hepatic drug metabolism.
Xenobiotica
; 50(11): 1370-1379, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32401667
3.
Organic Anion-Transporting Polypeptide (OATP)-Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver.
Drug Metab Dispos
; 46(1): 11-19, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29051147
4.
Novel pH-sensitive multifunctional envelope-type nanodevice for siRNA-based treatments for chronic HBV infection.
J Hepatol
; 64(3): 547-55, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26505121
5.
Murine Cyp3a knockout chimeric mice with humanized liver: prediction of the metabolic profile of nefazodone in humans.
Biopharm Drug Dispos
; 37(1): 3-14, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26352195
6.
Application of chimeric mice with humanized liver for study of human-specific drug metabolism.
Drug Metab Dispos
; 42(6): 1055-65, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24700822
7.
Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene.
Gut
; 62(9): 1340-6, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23135762
8.
Morphological and microarray analyses of human hepatocytes from xenogeneic host livers.
Lab Invest
; 93(1): 54-71, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23147226
9.
Chimeric mice with humanized livers: a unique tool for in vivo and in vitro enzyme induction studies.
Int J Mol Sci
; 15(1): 58-74, 2013 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24362577
10.
Investigation of drug-drug interactions caused by human pregnane X receptor-mediated induction of CYP3A4 and CYP2C subfamilies in chimeric mice with a humanized liver.
Drug Metab Dispos
; 40(3): 474-80, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22126990
11.
Freshly Isolated Hepatocytes from Chimeric Humanized Liver Mice for the In Vitro Assessment of Drug Metabolism, Inhibition/Induction, and Safety Studies.
Curr Protoc
; 2(5): e429, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35598301
12.
Characterization and Prevention of Hypovitaminosis C in Chimeric Mice with Humanized Livers.
Comp Med
; 72(6): 355-363, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36744513
13.
[In vivo and in vitro HBV infection model using chimeric mice with humanized livers].
Nihon Rinsho
; 73 Suppl 9: 386-91, 2015 Dec.
Artigo
em Japonês
| MEDLINE | ID: mdl-26845964
14.
Lipoprotein profile and lipid metabolism of PXB-cells®, human primary hepatocytes from liver-humanized mice: proposal of novel in vitro system for screening anti-lipidemic drugs.
Biomed Res
; 41(1): 33-42, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32092738
15.
Chimeric mice with human hepatocytes: A new system for genotoxicity studies.
Mutat Res Genet Toxicol Environ Mutagen
; 839: 9-12, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744813
16.
Chimeric Mice With Humanized Livers Demonstrate Human-Specific Hepatotoxicity Caused by a Therapeutic Antibody Against TRAIL-Receptor 2/Death Receptor 5.
Toxicol Sci
; 167(1): 190-201, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30202993
17.
Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection.
J Interferon Cytokine Res
; 39(3): 133-146, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30844328
18.
Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model.
ACS Infect Dis
; 5(5): 738-749, 2019 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30408957
19.
Lack of promoting effects of phenobarbital at low dose on diethylnitrosamine-induced hepatocarcinogenesis in TGF-alpha transgenic mice.
Asian Pac J Cancer Prev
; 7(2): 274-8, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16839222
20.
Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice.
PLoS One
; 10(11): e0142145, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26536627