Detalhe da pesquisa
1.
Mitochondrial oxidative stress contributes to the pathological aggregation and accumulation of tau oligomers in Alzheimer's disease.
Hum Mol Genet
; 31(15): 2498-2507, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165721
2.
Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein.
Biochem Soc Trans
; 52(1): 301-318, 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38348781
3.
TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau.
Proc Natl Acad Sci U S A
; 118(9)2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619090
4.
Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism.
J Neurosci
; 41(45): 9431-9451, 2021 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34607969
5.
EFhd2 brain interactome reveals its association with different cellular and molecular processes.
J Neurochem
; 159(6): 992-1007, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543436
6.
Clioquinol Decreases Levels of Phosphorylated, Truncated, and Oligomerized Tau Protein.
Int J Mol Sci
; 22(21)2021 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769495
7.
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils.
Neurobiol Dis
; 130: 104525, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276792
8.
Tau and Axonal Transport Misregulation in Tauopathies.
Adv Exp Med Biol
; 1184: 81-95, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32096030
9.
Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.
Neurobiol Dis
; 117: 125-136, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29859871
10.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 129, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716614
11.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 169, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843738
12.
Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies.
Am J Pathol
; 187(6): 1222-1229, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28413156
13.
Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization.
Int J Mol Sci
; 19(3)2018 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29562600
14.
Aging and Parkinson's disease: Different sides of the same coin?
Mov Disord
; 32(7): 983-990, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28520211
15.
Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies.
Neurobiol Dis
; 94: 18-31, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27260838
16.
Pioglitazone prevents tau oligomerization.
Biochem Biophys Res Commun
; 478(3): 1035-42, 2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27543203
17.
Soluble pre-fibrillar tau and ß-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline.
Acta Neuropathol
; 132(6): 875-895, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27770234
18.
Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.
Nat Rev Neurosci
; 12(6): 359-66, 2011 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21587290
19.
Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study.
Brain Inj
; 30(12): 1399-1413, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27834536
20.
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
Neurobiol Dis
; 82: 185-199, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26093169