Detalhe da pesquisa
1.
Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aß generation in Alzheimer's disease.
Acta Neuropathol
; 132(2): 235-256, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26993139
2.
The Alzheimer's ß-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.
Acta Neuropathol
; 126(3): 329-52, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23820808
3.
Identification and biology of ß-secretase.
J Neurochem
; 120 Suppl 1: 55-61, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22122287
4.
Melatonin Signal Transduction Pathways Require E-Box-Mediated Transcription of Per1 and Per2 to Reset the SCN Clock at Dusk.
PLoS One
; 11(6): e0157824, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27362940
5.
The normal and pathologic roles of the Alzheimer's ß-secretase, BACE1.
Curr Alzheimer Res
; 11(5): 441-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24893886
6.
The ß-secretase enzyme BACE1 as a therapeutic target for Alzheimer's disease.
Alzheimers Res Ther
; 3(3): 20, 2011 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21639952