Detalhe da pesquisa
1.
The N-terminal intrinsically disordered region of Ncb5or docks with the cytochrome b5 core to form a helical motif that is of ancient origin.
Proteins
; 92(4): 554-566, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38041394
2.
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection.
Proc Natl Acad Sci U S A
; 118(29)2021 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34210738
3.
Pseudomonas aeruginosa Dps (PA0962) Functions in H2O2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity.
Int J Mol Sci
; 24(5)2023 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36902100
4.
Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.
J Biol Chem
; 296: 100628, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33812994
5.
The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase.
J Virol
; 95(3)2021 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33158944
6.
Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection.
J Bacteriol
; 201(12)2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936373
7.
Mechanism-Based Macrocyclic Inhibitors of Serine Proteases.
J Med Chem
; 67(6): 4833-4854, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38477709
8.
Molecular basis for the activation of the Fatty Acid Kinase complex of Staphylococcus aureus.
bioRxiv
; 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38562735
9.
Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain.
Toxins (Basel)
; 15(7)2023 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37505680
10.
Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies.
ACS Pharmacol Transl Sci
; 6(1): 181-194, 2023 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36654747
11.
RNA structures and dynamics with Å resolution revealed by x-ray free-electron lasers.
Sci Adv
; 9(39): eadj3509, 2023 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37756398
12.
RNA structures and dynamics with Å resolution revealed by x-ray free electron lasers.
bioRxiv
; 2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292849
13.
Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease.
J Med Chem
; 65(11): 7818-7832, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35638577
14.
Structural insight into the novel iron-coordination and domain interactions of transferrin-1 from a model insect, Manduca sexta.
Protein Sci
; 30(2): 408-422, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33197096
15.
Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease.
J Med Chem
; 64(14): 10047-10058, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34213885
16.
Costameric integrin and sarcoglycan protein levels are altered in a Drosophila model for Limb-girdle muscular dystrophy type 2H.
Mol Biol Cell
; 32(3): 260-273, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33296226
17.
Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies.
J Med Chem
; 64(24): 17846-17865, 2021 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34865476
18.
Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain.
Toxins (Basel)
; 12(11)2020 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33171806
19.
Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease.
J Med Chem
; 63(20): 11945-11963, 2020 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32945669
20.
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice.
Sci Transl Med
; 12(557)2020 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747425