Detalhe da pesquisa
1.
Transcriptomic dysregulation and autistic-like behaviors in Kmt2c haploinsufficient mice rescued by an LSD1 inhibitor.
Mol Psychiatry
; 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38528071
2.
An ex vivo screening using mouse brain mitochondria identified seco-cycline D as an inhibitor of mitochondrial permeability transition pore.
Biochem Biophys Res Commun
; 691: 149253, 2024 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38043196
3.
GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice.
Mol Psychiatry
; 28(7): 2848-2856, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36806390
4.
Deep exome sequencing identifies enrichment of deleterious mosaic variants in neurodevelopmental disorder genes and mitochondrial tRNA regions in bipolar disorder.
Mol Psychiatry
; 28(10): 4294-4306, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37248276
5.
Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis.
Mol Psychiatry
; 28(5): 2039-2048, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36806762
6.
Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism.
Cell
; 137(7): 1235-46, 2009 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19563756
7.
Exploration of cell type-specific somatic mutations in schizophrenia and the impact of maternal immune activation on the somatic mutation profile in the brain.
Psychiatry Clin Neurosci
; 78(4): 237-247, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38334156
8.
Functional and behavioral effects of de novo mutations in calcium-related genes in patients with bipolar disorder.
Hum Mol Genet
; 30(19): 1851-1862, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34100076
9.
Brain-specific heterozygous loss-of-function of ATP2A2, endoplasmic reticulum Ca2+ pump responsible for Darier's disease, causes behavioral abnormalities and a hyper-dopaminergic state.
Hum Mol Genet
; 30(18): 1762-1772, 2021 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34104969
10.
Mood Stabilizers and Antipsychotics for Acute Mania: Systematic Review and Meta-Analysis of Augmentation Therapy vs Monotherapy From the Perspective of Time to the Onset of Treatment Effects.
Int J Neuropsychopharmacol
; 25(10): 839-852, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35932466
11.
Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder.
Mol Psychiatry
; 26(7): 3407-3418, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875800
12.
Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses.
Eur Arch Psychiatry Clin Neurosci
; 272(8): 1611-1620, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35146571
13.
Burden of schizophrenia among Japanese patients: a cross-sectional National Health and Wellness Survey.
BMC Psychiatry
; 22(1): 410, 2022 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35717149
14.
Cardiolipin is essential for early embryonic viability and mitochondrial integrity of neurons in mammals.
FASEB J
; 34(1): 1465-1480, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914590
15.
Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids.
Mol Psychiatry
; 25(11): 2695-2711, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32764691
16.
Impact of endogenous melatonin on rhythmic behaviors, reproduction, and survival revealed in melatonin-proficient C57BL/6J congenic mice.
J Pineal Res
; 71(2): e12748, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34085306
17.
Unbiased PCR-free spatio-temporal mapping of the mtDNA mutation spectrum reveals brain region-specific responses to replication instability.
BMC Biol
; 18(1): 150, 2020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097039
18.
Somatic mutations in the human brain: implications for psychiatric research.
Mol Psychiatry
; 24(6): 839-856, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30087451
19.
Double-blind, placebo-controlled study of lurasidone monotherapy for the treatment of bipolar I depression.
Psychiatry Clin Neurosci
; 74(12): 635-644, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32827348
20.
Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder.
Mol Psychiatry
; 23(10): 2039-2049, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29892051