Detalhe da pesquisa
1.
Sclerostin Antibody Reverses the Severe Sublesional Bone Loss in Rats After Chronic Spinal Cord Injury.
Calcif Tissue Int
; 103(4): 443-454, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29931461
2.
Anabolic Strategies to Augment Bone Fracture Healing.
Curr Osteoporos Rep
; 16(3): 289-298, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29725836
3.
Sclerostin Antibody Increases Callus Size and Strength but does not Improve Fracture Union in a Challenged Open Rat Fracture Model.
Calcif Tissue Int
; 101(2): 217-228, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28391431
4.
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation.
Nat Genet
; 37(9): 945-52, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16056226
5.
Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis.
Ann Rheum Dis
; 72(10): 1732-6, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23666928
6.
Dual Inhibition of the Wnt Inhibitors DKK1 and Sclerostin Promotes Fracture Healing and Increases the Density and Strength of Uninjured Bone: An Experimental Study in Nonhuman Primates.
J Bone Joint Surg Am
; 105(15): 1145-1155, 2023 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37159527
7.
Early response of bone marrow osteoprogenitors to skeletal unloading and sclerostin antibody.
Calcif Tissue Int
; 91(1): 50-8, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22644321
8.
IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation.
J Exp Med
; 201(7): 1169-77, 2005 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15809356
9.
Anti-sclerostin antibody and mechanical loading appear to influence metaphyseal bone independently in rats.
Acta Orthop
; 82(5): 628-32, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22103277
10.
Therapeutics for enhancement of spinal fusion: A mini review.
J Orthop Translat
; 31: 73-79, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34934624
11.
Osteocyte mechanosensing following short-term and long-term treatment with sclerostin antibody.
Bone
; 149: 115967, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33892178
12.
Recombinant sclerostin inhibits bone formation in vitro and in a mouse model of sclerosteosis.
J Orthop Translat
; 29: 134-142, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34249611
13.
Novel actions of sclerostin on bone.
J Mol Endocrinol
; 62(2): R167-R185, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30532996
14.
Retention of osteocytic micromorphology by sclerostin antibody in a concurrent ovariectomy and functional disuse model.
Ann N Y Acad Sci
; 1442(1): 91-103, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30644553
15.
Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts.
Bone
; 42(4): 644-52, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18291742
16.
Dampening of the bone formation response following repeat dosing with sclerostin antibody in mice is associated with up-regulation of Wnt antagonists.
Bone
; 107: 93-103, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29129759
17.
Sclerostin Antibody Reverses Bone Loss by Increasing Bone Formation and Decreasing Bone Resorption in a Rat Model of Male Osteoporosis.
Endocrinology
; 159(1): 260-271, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29069393
18.
Effects of sclerostin antibodies in animal models of osteoporosis.
Bone
; 96: 63-75, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27789417
19.
Sclerostin Antibody Administration Converts Bone Lining Cells Into Active Osteoblasts.
J Bone Miner Res
; 32(5): 892-901, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27862326
20.
Etelcalcetide (AMG 416), a peptide agonist of the calcium-sensing receptor, preserved cortical bone structure and bone strength in subtotal nephrectomized rats with established secondary hyperparathyroidism.
Bone
; 105: 163-172, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28867373