Detalhe da pesquisa
1.
Preclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12.
J Virol
; 86(9): 5304-13, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22379082
2.
CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infections.
Antimicrob Agents Chemother
; 55(10): 4728-34, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21788472
3.
Benzimidazole analogs inhibit human herpesvirus 6.
Antimicrob Agents Chemother
; 55(5): 2442-5, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300829
4.
Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase.
Antimicrob Agents Chemother
; 55(10): 4682-91, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21788463
5.
Efficacy of CMX001 against herpes simplex virus infections in mice and correlations with drug distribution studies.
J Infect Dis
; 202(10): 1492-9, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20923374
6.
Activities of certain 5-substituted 4'-thiopyrimidine nucleosides against orthopoxvirus infections.
Antimicrob Agents Chemother
; 53(2): 572-9, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19029322
7.
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
Antimicrob Agents Chemother
; 53(12): 5251-8, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19770274
8.
Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes.
J Virol
; 82(10): 5054-67, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18321963
9.
Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo.
Antimicrob Agents Chemother
; 52(8): 2727-33, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18505857
10.
Inhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates.
Antimicrob Agents Chemother
; 52(12): 4326-30, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18852272
11.
Effect of oral treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models.
Antiviral Res
; 79(2): 133-5, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18336926
12.
Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine.
Virol J
; 5: 39, 2008 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18321387
13.
Isolation and characterization of cidofovir resistant vaccinia viruses.
Virol J
; 5: 58, 2008 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18479513
14.
N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors.
J Med Chem
; 50(7): 1442-4, 2007 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17335190
15.
Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir.
Antiviral Res
; 75(1): 87-90, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17367874
16.
A rapid DNA hybridization assay for the evaluation of antiviral compounds against Epstein-Barr virus.
J Virol Methods
; 144(1-2): 86-90, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17540461
17.
Fluoroanalogues of anti-cytomegalovirus agent cyclopropavir: synthesis and antiviral activity of (E)- and (Z)-9-{[2,2-bis(hydroxymethyl)-3-fluorocyclopropylidene]methyl}-adenines and guanines.
Nucleosides Nucleotides Nucleic Acids
; 26(3): 231-43, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17454732
18.
Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS.
J Med Chem
; 49(3): 1140-8, 2006 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16451078
19.
5-(Dimethoxymethyl)-2'-deoxyuridine: a novel gem diether nucleoside with anti-orthopoxvirus activity.
J Med Chem
; 49(11): 3377-82, 2006 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16722657
20.
Toward orthopoxvirus countermeasures: a novel heteromorphic nucleoside of unusual structure.
J Med Chem
; 49(14): 4052-4, 2006 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16821766