Detalhe da pesquisa
1.
Brain Disposition of Antibody-Based Therapeutics: Dogma, Approaches and Perspectives.
Int J Mol Sci
; 22(12)2021 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34208575
2.
Lym-1 Chimeric Antigen Receptor T Cells Exhibit Potent Anti-Tumor Effects against B-Cell Lymphoma.
Int J Mol Sci
; 18(12)2017 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29261129
3.
Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics.
J Biol Chem
; 290(50): 29732-41, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491012
4.
Systemic delivery of chTNT-3/CpG immunoconjugates for immunotherapy in murine solid tumor models.
Cancer Immunol Immunother
; 65(5): 511-23, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26960932
5.
Comparative physiology of mice and rats: radiometric measurement of vascular parameters in rodent tissues.
Mol Pharm
; 11(5): 1591-8, 2014 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24702191
6.
Vascular physiology and protein disposition in a preclinical model of neurodegeneration.
Mol Pharm
; 10(5): 1514-21, 2013 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23383983
7.
Characterization of therapeutic monoclonal antibodies reveals differences between in vitro and in vivo time-course studies.
Pharm Res
; 30(1): 167-78, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22956170
8.
Enhancing brain entry and therapeutic activity of chimeric antigen receptor T cells with intra-arterial NEO100 in a mouse model of CNS lymphoma.
J Neurosurg
; : 1-9, 2023 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38157532
9.
Impact of drug conjugation on pharmacokinetics and tissue distribution of anti-STEAP1 antibody-drug conjugates in rats.
Bioconjug Chem
; 22(10): 1994-2004, 2011 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21913715
10.
Advances in Immuno-PET for the Detection of Cancer and Assessment of Response to Therapy.
Curr Med Chem
; 28(4): 647-672, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003655
11.
Spatio-temporal biodistribution of 89Zr-oxine labeled huLym-1-A-BB3z-CAR T-cells by PET imaging in a preclinical tumor model.
Sci Rep
; 11(1): 15077, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34302002
12.
Effects of charge on antibody tissue distribution and pharmacokinetics.
Bioconjug Chem
; 21(12): 2153-63, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21053952
13.
Development and evaluation of a novel method for preclinical measurement of tissue vascular volume.
Mol Pharm
; 7(5): 1848-57, 2010 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20704296
14.
Principles of N-Linked Glycosylation Variations of IgG-Based Therapeutics: Pharmacokinetic and Functional Considerations.
Antibodies (Basel)
; 9(2)2020 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32532067
15.
A Humanized Lym-1 CAR with Novel DAP10/DAP12 Signaling Domains Demonstrates Reduced Tonic Signaling and Increased Antitumor Activity in B-Cell Lymphoma Models.
Clin Cancer Res
; 26(14): 3694-3706, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32273277
16.
Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer.
Clin Cancer Res
; 14(2): 579-88, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18223234
17.
Biodistribution and efficacy of an anti-TENB2 antibody-drug conjugate in a patient-derived model of prostate cancer.
Oncotarget
; 10(58): 6234-6244, 2019 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31692898
18.
Drug delivery across the blood-brain barrier.
Mol Pharm
; 10(5): 1471-2, 2013 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23641922
19.
Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors.
Clin Cancer Res
; 13(9): 2758-67, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17460060
20.
Soluble Fc fusion proteins for biomedical research.
Methods Mol Biol
; 378: 33-52, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18605076