Detalhe da pesquisa
1.
An ERAD-independent role for rhomboid pseudoprotease Dfm1 in mediating sphingolipid homeostasis.
EMBO J
; 42(4): e112275, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350249
2.
Catalytic mechanism of trans-2-enoyl-CoA reductases in the fatty acid elongation cycle and its cooperative action with fatty acid elongases.
J Biol Chem
; 300(2): 105656, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38224948
3.
Ceramide synthase homolog Tlc4 maintains nuclear envelope integrity via its Golgi translocation.
J Cell Sci
; 136(10)2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37078207
4.
Alteration of epidermal lipid composition as a result of deficiency in the magnesium transporter Nipal4.
J Lipid Res
; 65(6): 100550, 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38692573
5.
Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine ceramides.
J Biol Chem
; 299(4): 104603, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36907437
6.
Formation of fatty alcohols-components of meibum lipids-by the fatty acyl-CoA reductase FAR2 is essential for dry eye prevention.
FASEB J
; 36(4): e22216, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35238077
7.
Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid ω-O-acylceramide.
Proc Natl Acad Sci U S A
; 117(6): 2914-2922, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31974308
8.
Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases.
J Lipid Res
; 63(7): 100235, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35654151
9.
Ceramide Analysis in Combination With Genetic Testing May Provide a Precise Diagnosis for Self-Healing Collodion Babies.
J Lipid Res
; 63(12): 100308, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36332686
10.
Direct uptake of sphingosine-1-phosphate independent of phospholipid phosphatases.
J Biol Chem
; 296: 100605, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33785361
11.
The very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function in fission yeast cells.
J Cell Sci
; 132(10)2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975915
12.
Amlexanox enhances the antitumor effect of anti-PD-1 antibody.
Biochem Biophys Res Commun
; 560: 1-6, 2021 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33965784
13.
Biosynthesis of the anti-lipid-microdomain sphingoid base 4,14-sphingadiene by the ceramide desaturase FADS3.
FASEB J
; 34(2): 3318-3335, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31916624
14.
Comparative profiling and comprehensive quantification of stratum corneum ceramides in humans and mice by LC/MS/MS.
J Lipid Res
; 61(6): 884-895, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32265320
15.
Catalytic residues, substrate specificity, and role in carbon starvation of the 2-hydroxy FA dioxygenase Mpo1 in yeast.
J Lipid Res
; 61(7): 1104-1114, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32350077
16.
N-glycosylation of Rim21 at an Unconventional Site Fine-tunes Its Behavior in the Plasma Membrane.
Cell Struct Funct
; 45(1): 1-8, 2020 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31787665
17.
Neural symptoms in a gene knockout mouse model of Sjögren-Larsson syndrome are associated with a decrease in 2-hydroxygalactosylceramide.
FASEB J
; 33(1): 928-941, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30085884
18.
The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway.
Mol Cell
; 46(4): 461-71, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22633490
19.
De novo mutation in ELOVL1 causes ichthyosis, acanthosis nigricans, hypomyelination, spastic paraplegia, high frequency deafness and optic atrophy.
J Med Genet
; 56(3): 164-175, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30487246
20.
Phytosphingosine degradation pathway includes fatty acid α-oxidation reactions in the endoplasmic reticulum.
Proc Natl Acad Sci U S A
; 114(13): E2616-E2623, 2017 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28289220