Detalhe da pesquisa
1.
Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a.
PLoS Genet
; 17(12): e1009934, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34914716
2.
Cellular and molecular characterization of two novel asparagine synthetase gene mutations linked to asparagine synthetase deficiency.
J Biol Chem
; 298(9): 102385, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35985424
3.
Analysis of Enzyme Activity and Cellular Function for the N80S and S480F Asparagine Synthetase Variants Expressed in a Child with Asparagine Synthetase Deficiency.
Int J Mol Sci
; 24(1)2022 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36613999
4.
The role of asparagine synthetase on nutrient metabolism in pancreatic disease.
Pancreatology
; 20(6): 1029-1034, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32800652
5.
Asparagine synthetase: Function, structure, and role in disease.
J Biol Chem
; 292(49): 19952-19958, 2017 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29084849
6.
Characterization of a novel variant in siblings with Asparagine Synthetase Deficiency.
Mol Genet Metab
; 123(3): 317-325, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29279279
7.
The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation.
Nucleic Acids Res
; 44(20): 9719-9732, 2016 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27471030
8.
Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element.
J Biol Chem
; 290(25): 15878-15891, 2015 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25931127
9.
MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells.
Biochim Biophys Acta
; 1853(3): 539-48, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25523140
10.
Genomic and proteomic analysis of transcription factor TFII-I reveals insight into the response to cellular stress.
Nucleic Acids Res
; 42(12): 7625-41, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24875474
11.
A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation.
J Biol Chem
; 289(35): 24665-79, 2014 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25028509
12.
Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.
Mol Genet Metab
; 116(3): 178-86, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26318253
13.
Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation.
Biochem J
; 449(1): 219-29, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22978410
14.
Elevated cJUN expression and an ATF/CRE site within the ATF3 promoter contribute to activation of ATF3 transcription by the amino acid response.
Physiol Genomics
; 45(4): 127-37, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23269699
15.
ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.
J Biol Chem
; 287(43): 36393-403, 2012 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22955275
16.
Asparagine synthetase: regulation by cell stress and involvement in tumor biology.
Am J Physiol Endocrinol Metab
; 304(8): E789-99, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403946
17.
Activation of the amino acid response modulates lineage specification during differentiation of murine embryonic stem cells.
Am J Physiol Endocrinol Metab
; 305(3): E325-35, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23736538
18.
A method for measurement of human asparagine synthetase (ASNS) activity and application to ASNS protein variants associated with ASNS deficiency.
Biol Methods Protoc
; 8(1): bpad026, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37965492
19.
Utility of AlphaMissense predictions in Asparagine Synthetase deficiency variant classification.
bioRxiv
; 2023 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961642
20.
Characterizing asparagine synthetase deficiency variants in lymphoblastoid cell lines.
JIMD Rep
; 64(2): 167-179, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36873094