Detalhe da pesquisa
1.
Distinct lateral hypothalamic CaMKIIα neuronal populations regulate wakefulness and locomotor activity.
Proc Natl Acad Sci U S A
; 121(16): e2316150121, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593074
2.
Activation of the nociceptin/orphanin-FQ receptor promotes NREM sleep and EEG slow wave activity.
Proc Natl Acad Sci U S A
; 120(13): e2214171120, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36947514
3.
Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy.
Proc Natl Acad Sci U S A
; 120(41): e2301951120, 2023 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37796986
4.
Biological sex influences sleep phenotype in mice experiencing spontaneous opioid withdrawal.
J Sleep Res
; : e14037, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37731248
5.
Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK-925 and ARN-776 in narcoleptic orexin/tTA; TetO-DTA mice.
J Sleep Res
; 32(4): e13839, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36808670
6.
Transgenic Archaerhodopsin-3 Expression in Hypocretin/Orexin Neurons Engenders Cellular Dysfunction and Features of Type 2 Narcolepsy.
J Neurosci
; 39(47): 9435-9452, 2019 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31628177
7.
Excitation of Cortical nNOS/NK1R Neurons by Hypocretin 1 is Independent of Sleep Homeostasis.
Cereb Cortex
; 29(3): 1090-1108, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29462275
8.
Cortical nNOS/NK1 Receptor Neurons are Regulated by Cholinergic Projections From the Basal Forebrain.
Cereb Cortex
; 28(6): 1959-1979, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472227
9.
Mapping the Hypocretin/Orexin Neuronal System: An Unexpectedly Productive Journey.
J Neurosci
; 37(9): 2268-2272, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250055
10.
A role for cortical nNOS/NK1 neurons in coupling homeostatic sleep drive to EEG slow wave activity.
Proc Natl Acad Sci U S A
; 110(50): 20272-7, 2013 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24191004
11.
GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy.
J Neurosci
; 34(19): 6485-94, 2014 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24806675
12.
Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function.
J Neurosci
; 34(19): 6495-509, 2014 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24806676
13.
Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation.
J Neurosci
; 34(20): 6896-909, 2014 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24828644
14.
Pharmacology of basimglurant (RO4917523, RG7090), a unique metabotropic glutamate receptor 5 negative allosteric modulator in clinical development for depression.
J Pharmacol Exp Ther
; 353(1): 213-33, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25665805
15.
Longitudinal analysis of the electroencephalogram and sleep phenotype in the R6/2 mouse model of Huntington's disease.
Brain
; 136(Pt 7): 2159-72, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23801738
16.
H1N1 infection of sleep/wake regions results in narcolepsy-like symptoms.
Proc Natl Acad Sci U S A
; 113(3): 476-7, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26747601
17.
Peripheral vs. core body temperature as hypocretin/orexin neurons degenerate: Exercise mitigates increased heat loss.
Peptides
; 164: 171002, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36963505
18.
Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice.
J Neurosci
; 31(29): 10529-39, 2011 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21775598
19.
Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture.
Proc Natl Acad Sci U S A
; 106(11): 4459-64, 2009 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19246384
20.
The development of sleep/wake disruption and cataplexy as hypocretin/orexin neurons degenerate in male vs. female Orexin/tTA; TetO-DTA Mice.
Sleep
; 45(12)2022 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35182424