Detalhe da pesquisa
1.
2,2'-Bithiophene as sensor tag for ligand-protein binding assays based on Förster resonance energy transfer.
Anal Biochem
; 682: 115335, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37777080
2.
Nasally delivered VEGFD mimetics mitigate stroke-induced dendrite loss and brain damage.
Proc Natl Acad Sci U S A
; 117(15): 8616-8623, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229571
3.
The spectrum between substrates and inhibitors: Pinpointing the binding mode of dengue protease ligands with modulated basicity and hydrophobicity.
Bioorg Med Chem
; 48: 116412, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34592636
4.
Backbone modifications in peptidic inhibitors of flaviviral proteases.
Bioorg Med Chem Lett
; 29(15): 1913-1917, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31176698
5.
Inhibitor potency and assay conditions: A case study on SARS-CoV-2 main protease.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475216
6.
Sensitive NMR Approach for Determining the Binding Mode of Tightly Binding Ligand Molecules to Protein Targets.
J Am Chem Soc
; 138(13): 4539-46, 2016 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26974502
7.
N-Terminal methionine processing by the zinc-activated Plasmodium falciparum methionine aminopeptidase 1b.
Appl Microbiol Biotechnol
; 100(16): 7091-102, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27023914
8.
Dual inhibitors of the dengue and West Nile virus NS2B-NS3 proteases: Synthesis, biological evaluation and docking studies of novel peptide-hybrids.
Bioorg Med Chem
; 23(17): 5748-55, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26233795
9.
Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases.
Bioorg Med Chem Lett
; 24(22): 5310-4, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25293447
10.
Alternate recognition by dengue protease: Proteolytic and binding assays provide functional evidence beyond an induced-fit.
Biochimie
; 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38871044
11.
Chemical, biochemical and microbiological properties of a brominated nitrovinylfuran with broad-spectrum antibacterial activity.
Bioorg Med Chem
; 21(3): 795-804, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23266177
12.
N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors.
Eur J Med Chem
; 251: 115227, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36893626
13.
Corona versus Dengue: Distinct Mechanisms for Inhibition of Polyprotein Processing by Antiviral Drugs.
ACS Pharmacol Transl Sci
; 5(7): 508-511, 2022 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35837137
14.
Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases.
Eur J Med Chem
; 240: 114585, 2022 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863275
15.
Biochemistry and medicinal chemistry of the dengue virus protease.
Chem Rev
; 114(22): 11348-81, 2014 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25268322
16.
Arylcyanoacrylamides as inhibitors of the Dengue and West Nile virus proteases.
Bioorg Med Chem
; 19(24): 7318-37, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22094280
17.
Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture.
Bioorg Med Chem
; 19(13): 4067-74, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21641807
18.
On track to tackle dengue: History and future of NS4B ligands.
Cell Host Microbe
; 29(12): 1735-1737, 2021 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34883063
19.
Efficiency Improvements and Discovery of New Substrates for a SARS-CoV-2 Main Protease FRET Assay.
SLAS Discov
; 26(9): 1189-1199, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34151620
20.
Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture.
J Med Chem
; 64(8): 4567-4587, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851839