Detalhe da pesquisa
1.
Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease.
N Engl J Med
; 387(20): 1855-1864, 2022 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36342163
2.
Study design and rationale for the Olpasiran trials of Cardiovascular Events And lipoproteiN(a) reduction-DOSE finding study (OCEAN(a)-DOSE).
Am Heart J
; 251: 61-69, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35588897
3.
Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 as monotherapy in patients with hypercholesterolaemia (MENDEL): a randomised, double-blind, placebo-controlled, phase 2 study.
Lancet
; 380(9858): 1995-2006, 2012 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23141812
4.
LDL-cholesterol lowering with evolocumab, and outcomes according to age and sex in patients in the FOURIER Trial.
Eur J Prev Cardiol
; 28(8): 805-812, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298555
5.
Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia.
Circulation
; 117(4): 526-35, 2008 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18195176
6.
Effect of evolocumab on lipoprotein apheresis requirement and lipid levels: Results of the randomized, controlled, open-label DE LAVAL study.
J Clin Lipidol
; 13(6): 901-909.e3, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31759938
7.
Acute Treatment With Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure: The ATOMIC-AHF Study.
J Am Coll Cardiol
; 67(12): 1444-1455, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27012405
8.
Anti-PCSK9 antibody effectively lowers cholesterol in patients with statin intolerance: the GAUSS-2 randomized, placebo-controlled phase 3 clinical trial of evolocumab.
J Am Coll Cardiol
; 63(23): 2541-2548, 2014 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24694531
9.
Design and rationale of the LAPLACE-TIMI 57 trial: a phase II, double-blind, placebo-controlled study of the efficacy and tolerability of a monoclonal antibody inhibitor of PCSK9 in subjects with hypercholesterolemia on background statin therapy.
Clin Cardiol
; 35(7): 385-91, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22714699
10.
The safety and tolerability of darbepoetin alfa in patients with anaemia and symptomatic heart failure.
Eur J Heart Fail
; 11(11): 1071-7, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19815661