Detalhe da pesquisa
1.
Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity.
Nat Immunol
; 23(4): 568-580, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314846
2.
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell
; 179(2): 417-431.e19, 2019 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31585081
3.
Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1.
Immunity
; 54(7): 1511-1526.e8, 2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34260887
4.
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell
; 180(2): 406, 2020 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31978350
5.
Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action.
J Biol Chem
; 299(1): 102729, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410439
6.
Application of N-Terminal Site-Specific Biotin and Digoxigenin Conjugates to Clinical Anti-drug Antibody Assay Development.
Bioconjug Chem
; 35(2): 174-186, 2024 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050929
7.
Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function.
Proc Natl Acad Sci U S A
; 118(12)2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33723046
8.
High-Throughput Analyses of Therapeutic Antibodies Using High-Field Asymmetric Waveform Ion Mobility Spectrometry Combined with SampleStream and Intact Protein Mass Spectrometry.
Anal Chem
; 95(47): 17263-17272, 2023 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37956201
9.
Development of an 18F-labeled anti-human CD8 VHH for same-day immunoPET imaging.
Eur J Nucl Med Mol Imaging
; 50(3): 679-691, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346438
10.
Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma.
J Allergy Clin Immunol
; 150(4): 972-978.e7, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35487308
11.
Development of an SPR-based binding assay for characterization of anti-CD20 antibodies to CD20 expressed on extracellular vesicles.
Anal Biochem
; 646: 114635, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35278435
12.
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
Mol Cell
; 56(3): 360-375, 2014 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25284222
13.
Monoclonal antibody targeting the ß-barrel assembly machine of Escherichia coli is bactericidal.
Proc Natl Acad Sci U S A
; 115(14): 3692-3697, 2018 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29555747
14.
The Escherichia coli ß-Barrel Assembly Machinery Is Sensitized to Perturbations under High Membrane Fluidity.
J Bacteriol
; 201(1)2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322857
15.
Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation.
Proc Natl Acad Sci U S A
; 110(21): 8477-82, 2013 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23650375
16.
Preclinical and translational pharmacology of afucosylated anti-CCR8 antibody for depletion of tumour-infiltrating regulatory T cells.
Br J Pharmacol
; 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38486310
17.
A novel, label-free, pre-equilibrium assay to determine the association and dissociation rate constants of therapeutic antibodies on living cells.
Br J Pharmacol
; 2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783572
18.
Mini-PBPK-Based Population Model and Covariate Analysis to Assess the Complex Pharmacokinetics and Pharmacodynamics of RO7449135, an Anti-KLK5/KLK7 Bispecific Antibody in Cynomolgus Monkeys.
AAPS J
; 25(4): 64, 2023 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37353723
19.
Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun
; 14(1): 7940, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38040762
20.
Combined PD-L1/TGFß blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors.
Nat Commun
; 14(1): 4703, 2023 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37543621