Detalhe da pesquisa
1.
Synthesis and SAR of sulfoxide substituted carboxyquinolines as NK3 receptor antagonists.
Bioorg Med Chem Lett
; 21(6): 1896-9, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21320776
2.
SAR development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as kappa opioid receptor antagonists. Part 2.
Bioorg Med Chem Lett
; 20(18): 5405-10, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20719509
3.
Discovery of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as selective antagonists of the kappa opioid receptor. Part 1.
Bioorg Med Chem Lett
; 20(19): 5847-52, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20727752
4.
4-aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators.
Bioorg Med Chem Lett
; 20(24): 7381-4, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21067920
5.
Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency.
J Med Chem
; 50(24): 5912-25, 2007 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-17985862
6.
Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity.
J Med Chem
; 45(18): 3972-83, 2002 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-12190319
7.
Naphtho[2,1-b][1,5] and [1,2-f][1,4]oxazocines as selective NK1 antagonists.
Bioorg Med Chem
; 12(10): 2653-69, 2004 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15110847