Detalhe da pesquisa
1.
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity.
Nature
; 575(7781): 217-223, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31666701
2.
Method development of a novel PK assay for antibody-conjugated drug measurement of ADCs using peptide-linker drug analyte.
Anal Bioanal Chem
; 411(12): 2587-2596, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30828756
3.
Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.
J Pharmacokinet Pharmacodyn
; 44(6): 537-548, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28918591
4.
An anti-B7-H4 antibody-drug conjugate for the treatment of breast cancer.
Mol Pharm
; 12(6): 1717-29, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25853436
5.
Semi-mechanistic Multiple-Analyte Pharmacokinetic Model for an Antibody-Drug-Conjugate in Cynomolgus Monkeys.
Pharm Res
; 32(6): 1907-19, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25467958
6.
Impact of drug conjugation on pharmacokinetics and tissue distribution of anti-STEAP1 antibody-drug conjugates in rats.
Bioconjug Chem
; 22(10): 1994-2004, 2011 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21913715
7.
Hypoxia Attenuates Trastuzumab Uptake and Trastuzumab-Emtansine (T-DM1) Cytotoxicity through Redistribution of Phosphorylated Caveolin-1.
Mol Cancer Res
; 18(4): 644-656, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900313
8.
Minimal physiologically-based pharmacokinetic modeling of DSTA4637A, A novel THIOMAB™ antibody antibiotic conjugate against Staphylococcus aureus, in a mouse model.
MAbs
; 10(7): 1131-1143, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30081725
9.
Pharmacokinetics and pharmacodynamics of DSTA4637A: A novel THIOMAB™ antibody antibiotic conjugate against Staphylococcus aureus in mice.
MAbs
; 8(8): 1612-1619, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27653831