Detalhe da pesquisa
1.
Increased flexibility of the SARS-CoV-2 RNA-binding site causes resistance to remdesivir.
PLoS Pathog
; 19(3): e1011231, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972312
2.
Impact of sarcopenia in patients with advanced or recurrent colorectal cancer treated with regorafenib.
Int J Clin Oncol
; 26(2): 409-416, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33104907
3.
Mitochondrial pyruvate carrier 1 expression controls cancer epithelial-mesenchymal transition and radioresistance.
Cancer Sci
; 110(4): 1331-1339, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30801869
4.
Clinical Significance of Histone Demethylase NO66 in Invasive Colorectal Cancer.
Ann Surg Oncol
; 24(3): 841-849, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27473587
5.
Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition.
Proc Natl Acad Sci U S A
; 111(43): 15526-31, 2014 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313085
6.
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor.
Proc Natl Acad Sci U S A
; 110(40): 15892-7, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24043811
7.
Molecular Orbital Study of the Formation of Intramolecular Hydrogen Bonding of a Ligand Molecule in a Protein Aromatic Hydrophobic Pocket.
Chem Pharm Bull (Tokyo)
; 64(7): 1031-5, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27373666
8.
Susceptibility of pancreatic cancer stem cells to reprogramming.
Cancer Sci
; 106(9): 1182-7, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26298849
9.
Prognostic Impact of Peritumoral IL-17-Positive Cells and IL-17 Axis in Patients with Intrahepatic Cholangiocarcinoma.
Ann Surg Oncol
; 22 Suppl 3: S1524-31, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26228109
10.
Design and Synthesis of Labystegines, Hybrid Iminosugars from LAB and Calystegine, as Inhibitors of Intestinal α-Glucosidases: Binding Conformation and Interaction for ntSI.
J Org Chem
; 80(9): 4501-15, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25843107
11.
[Therapeutic Implication Targeting for Cancer Stem Cells].
Gan To Kagaku Ryoho
; 42(9): 1036-9, 2015 Sep.
Artigo
em Japonês
| MEDLINE | ID: mdl-26469158
12.
Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis.
Cancer Sci
; 105(9): 1100-8, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25060325
13.
Cancer stem cells of the digestive system.
Jpn J Clin Oncol
; 44(12): 1141-9, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425726
14.
Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis.
EBioMedicine
; 103: 105102, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38614865
15.
Topological data analysis of protein structure and inter/intra-molecular interaction changes attributable to amino acid mutations.
Comput Struct Biotechnol J
; 21: 2950-2959, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37228703
16.
Metastases and treatment-resistant lineages in patient-derived cancer cells of colorectal cancer.
Commun Biol
; 6(1): 1191, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37996567
17.
Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway.
Nat Commun
; 14(1): 7048, 2023 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37923722
18.
Spatial and single-cell transcriptomics decipher the cellular environment containing HLA-G+ cancer cells and SPP1+ macrophages in colorectal cancer.
Cell Rep
; 42(1): 111929, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36656712
19.
Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-ß-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1.
Bioorg Med Chem
; 20(1): 356-67, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22104435
20.
Bayesian statistical method for detecting structural and topological diversity in polymorphic proteins.
Comput Struct Biotechnol J
; 20: 6519-6525, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36467576