Detalhe da pesquisa
1.
Distinct hemodynamic responses to (pyr)apelin-13 in large animal models.
Am J Physiol Heart Circ Physiol
; 318(4): H747-H755, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32108522
2.
Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats.
J Pharmacol Exp Ther
; 362(1): 108-118, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28465372
3.
Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody.
J Lipid Res
; 56(11): 2124-32, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26392590
4.
Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion.
J Biol Chem
; 288(9): 6386-96, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23322769
5.
Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models.
PLoS One
; 19(1): e0292091, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38277356
6.
Acute SGLT-2i treatment improves cardiac efficiency during myocardial ischemia independent of Na+/H+ exchanger-1.
Int J Cardiol
; 363: 138-148, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35753619
7.
Effects of pharmacological inhibition of the sodium-dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models.
Pharmacol Res Perspect
; 10(2): e00938, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35194979
8.
The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay.
J Pharmacol Exp Ther
; 325(3): 723-31, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18326812
9.
The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins.
J Pharmacol Exp Ther
; 324(2): 576-86, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17986646
10.
Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors.
Bioorg Med Chem Lett
; 18(3): 1151-6, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18155906
11.
A nonpeptide, piperidine renin inhibitor provides renal and cardiac protection in double-transgenic mice expressing human renin and angiotensinogen genes.
Cardiovasc Drugs Ther
; 22(6): 469-78, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18679781
12.
Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice.
Sci Rep
; 8(1): 16077, 2018 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30356054
13.
Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice.
Sci Rep
; 7(1): 492, 2017 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28352088
14.
Dual angiotensin II and endothelin A receptor antagonists: synthesis of 2'-substituted N-3-isoxazolyl biphenylsulfonamides with improved potency and pharmacokinetics.
J Med Chem
; 48(1): 171-9, 2005 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-15634011
15.
Discovery of N-isoxazolyl biphenylsulfonamides as potent dual angiotensin II and endothelin A receptor antagonists.
J Med Chem
; 45(18): 3829-35, 2002 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-12190306
16.
Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms.
PLoS One
; 9(1): e86522, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24475136
17.
Opportunities for pharmacotherapy at the intersection of metabolic syndrome and hemostasis.
Curr Pharm Biotechnol
; 12(9): 1463-80, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21401518
18.
Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease.
Endocr Metab Immune Disord Drug Targets
; 8(4): 238-43, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19075777
19.
Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice.
Pharmacol Res
; 58(1): 45-51, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18611440
20.
Pyrazole inhibitors of HMG-CoA reductase: an attempt to dramatically reduce synthetic complexity through minimal analog re-design.
Bioorg Med Chem Lett
; 17(20): 5567-72, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17764936