Detalhe da pesquisa
1.
Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells.
Mol Cell Proteomics
; 17(12): 2434-2447, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30217950
2.
Polypharmacology-based ceritinib repurposing using integrated functional proteomics.
Nat Chem Biol
; 13(12): 1222-1231, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28991240
3.
APOSTL: An Interactive Galaxy Pipeline for Reproducible Analysis of Affinity Proteomics Data.
J Proteome Res
; 15(12): 4747-4754, 2016 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27680298
4.
Unraveling the rewired network.
Nat Chem Biol
; 14(8): 746-747, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29942077
5.
De novo generation of multi-target compounds using deep generative chemistry.
Nat Commun
; 15(1): 3636, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710699
6.
IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells.
Sci Signal
; 15(747): eabj5879, 2022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35973030
7.
Interpretation of cancer mutations using a multiscale map of protein systems.
Science
; 374(6563): eabf3067, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591613
8.
A census of pathway maps in cancer systems biology.
Nat Rev Cancer
; 20(4): 233-246, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32066900
9.
Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells.
Cancer Cell
; 38(5): 672-684.e6, 2020 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33096023
10.
Off-target based drug repurposing opportunities for tivantinib in acute myeloid leukemia.
Sci Rep
; 9(1): 606, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30679640
11.
The Galaxy Platform for Reproducible Affinity Proteomic Mass Spectrometry Data Analysis.
Methods Mol Biol
; 1977: 249-261, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30980333
12.
An immunoproteomic approach to characterize the CAR interactome and signalosome.
Sci Signal
; 12(568)2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30755478
13.
Ceritinib Enhances the Efficacy of Trametinib in BRAF/NRAS-Wild-Type Melanoma Cell Lines.
Mol Cancer Ther
; 17(1): 73-83, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133622
14.
Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer.
Mol Cancer Ther
; 17(12): 2796-2810, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30242092
15.
Escape Excel: A tool for preventing gene symbol and accession conversion errors.
PLoS One
; 12(9): e0185207, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28953918
16.
Sustained activation of the AKT/mTOR and MAP kinase pathways mediate resistance to the Src inhibitor, dasatinib, in thyroid cancer.
Oncotarget
; 8(61): 103014-103031, 2017 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29262541
17.
Author Correction: A census of pathway maps in cancer systems biology.
Nat Rev Cancer
; 21(3): 212, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33441978
18.
Proteome-wide Profiling of Clinical PARP Inhibitors Reveals Compound-Specific Secondary Targets.
Cell Chem Biol
; 23(12): 1490-1503, 2016 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27866910
19.
Chemoproteomics Reveals Novel Protein and Lipid Kinase Targets of Clinical CDK4/6 Inhibitors in Lung Cancer.
ACS Chem Biol
; 10(12): 2680-6, 2015 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26390342
20.
GSK3 alpha and beta are new functionally relevant targets of tivantinib in lung cancer cells.
ACS Chem Biol
; 9(2): 353-8, 2014 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24215125