Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection.

Lin, Xiaoyuan; Fu, Beibei; Xiong, Yan; Xing, Na; Xue, Weiwei; Guo, Dong; Zaky, Mohamed; Pavani, Krishna; Kunec, Dusan; Trimpert, Jakob; Wu, Haibo.

PLoS Pathog ; 19(1): e1011128, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36689483

2.

A non-transmissible live attenuated SARS-CoV-2 vaccine.

Adler, Julia M; Martin Vidal, Ricardo; Voß, Anne; Kunder, Sandra; Nascimento, Mariana; Abdelgawad, Azza; Langner, Christine; Vladimirova, Daria; Osterrieder, Nikolaus; Gruber, Achim D; Kunec, Dusan; Trimpert, Jakob.

Mol Ther ; 31(8): 2391-2407, 2023 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-37263272

3.

Engineering and Characterization of Avian Coronavirus Mutants Expressing Fluorescent Reporter Proteins from the Replicase Gene.

Xing, Na; Wang, Zhisheng; Wang, Jichun; Nascimento, Mariana; Jongkaewwattana, Anan; Trimpert, Jakob; Osterrieder, Nikolaus; Kunec, Dusan.

J Virol ; 96(14): e0065322, 2022 07 27.

Artigo em Inglês | MEDLINE | ID: mdl-35862676

4.

Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization.

Eschke, Kathrin; Trimpert, Jakob; Osterrieder, Nikolaus; Kunec, Dusan.

PLoS Pathog ; 14(1): e1006857, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29377958

5.

Isolation and characterization of new Puumala orthohantavirus strains from Germany.

Binder, Florian; Reiche, Sven; Roman-Sosa, Gleyder; Saathoff, Marion; Ryll, René; Trimpert, Jakob; Kunec, Dusan; Höper, Dirk; Ulrich, Rainer G.

Virus Genes ; 56(4): 448-460, 2020 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-32328924

6.

Codon pair bias deoptimization of the major oncogene meq of a very virulent Marek's disease virus.

Khedkar, Pratik Hemant; Osterrieder, Nikolaus; Kunec, Dusan.

J Gen Virol ; 99(12): 1705-1716, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30113295

7.

Co-translational processing of glycoprotein 3 from equine arteritis virus: N-glycosylation adjacent to the signal peptide prevents cleavage.

Matczuk, Anna Karolina; Kunec, Dusan; Veit, Michael.

J Biol Chem ; 288(49): 35396-405, 2013 Dec 06.

Artigo em Inglês | MEDLINE | ID: mdl-24142700

8.

An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission.

Adler, Julia M; Martin Vidal, Ricardo; Langner, Christine; Vladimirova, Daria; Abdelgawad, Azza; Kunecova, Daniela; Lin, Xiaoyuan; Nouailles, Geraldine; Voss, Anne; Kunder, Sandra; Gruber, Achim D; Wu, Haibo; Osterrieder, Nikolaus; Kunec, Dusan; Trimpert, Jakob.

Nat Commun ; 15(1): 995, 2024 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-38307868

9.

Proteomics applied to avian herpesviruses.

Kunec, Dusan.

Avian Dis ; 57(2 Suppl): 351-9, 2013 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-23901746

10.

The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage.

Lin, Xiaoyuan; Sha, Zhou; Trimpert, Jakob; Kunec, Dusan; Jiang, Chen; Xiong, Yan; Xu, Binbin; Zhu, Zhenglin; Xue, Weiwei; Wu, Haibo.

Cell Host Microbe ; 31(7): 1170-1184.e7, 2023 07 12.

Artigo em Inglês | MEDLINE | ID: mdl-37402373

11.

Pet Rats as the Likely Reservoir for Human Seoul Orthohantavirus Infection.

Heuser, Elisa; Drewes, Stephan; Trimpert, Jakob; Kunec, Dusan; Mehl, Calvin; de Cock, Marieke P; de Vries, Ankje; Klier, Christiane; Oskamp, Martin; Tenhaken, Peter; Hashemi, Fatima; Heinz, Daniela; Nascimento, Mariana; Boelhauve, Marc; Petraityte-Burneikiene, Rasa; Raafat, Dina; Maas, Miriam; Krüger, Detlev H; Latz, Andreas; Hofmann, Jörg; Heckel, Gerald; Dreesman, Johannes; Ulrich, Rainer G.

Viruses ; 15(2)2023 02 07.

Artigo em Inglês | MEDLINE | ID: mdl-36851681

12.

Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.

Nouailles, Geraldine; Adler, Julia M; Pennitz, Peter; Peidli, Stefan; Teixeira Alves, Luiz Gustavo; Baumgardt, Morris; Bushe, Judith; Voss, Anne; Langenhagen, Alina; Langner, Christine; Martin Vidal, Ricardo; Pott, Fabian; Kazmierski, Julia; Ebenig, Aileen; Lange, Mona V; Mühlebach, Michael D; Goekeri, Cengiz; Simmons, Szandor; Xing, Na; Abdelgawad, Azza; Herwig, Susanne; Cichon, Günter; Niemeyer, Daniela; Drosten, Christian; Goffinet, Christine; Landthaler, Markus; Blüthgen, Nils; Wu, Haibo; Witzenrath, Martin; Gruber, Achim D; Praktiknjo, Samantha D; Osterrieder, Nikolaus; Wyler, Emanuel; Kunec, Dusan; Trimpert, Jakob.

Nat Microbiol ; 8(5): 860-874, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37012419

13.

Synthetically recoded virus sCPD9 - A tool to accelerate SARS-CoV-2 research under biosafety level 2 conditions.

Kunec, Dusan; Osterrieder, Nikolaus; Trimpert, Jakob.

Comput Struct Biotechnol J ; 20: 4376-4380, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35992535

14.

Zoonotic pathogen screening of striped field mice (Apodemus agrarius) from Austria.

Jeske, Kathrin; Herzig-Straschil, Barbara; Raileanu, Cristian; Kunec, Dusan; Tauchmann, Oliver; Emirhar, Duygu; Schmidt, Sabrina; Trimpert, Jakob; Silaghi, Cornelia; Heckel, Gerald; Ulrich, Rainer G; Drewes, Stephan.

Transbound Emerg Dis ; 69(2): 886-890, 2022 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-33534959

15.

Fast-forwarding evolution-Accelerated adaptation in a proofreading-deficient hypermutator herpesvirus.

Xing, Na; Höfler, Thomas; Hearn, Cari J; Nascimento, Mariana; Camps Paradell, Georgina; McMahon, Dino P; Kunec, Dusan; Osterrieder, Nikolaus; Cheng, Hans H; Trimpert, Jakob.

Virus Evol ; 8(2): veac099, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36405341

16.

ACE2-Variants Indicate Potential SARS-CoV-2-Susceptibility in Animals: A Molecular Dynamics Study.

Pach, Szymon; Nguyen, Trung Ngoc; Trimpert, Jakob; Kunec, Dusan; Osterrieder, Nikolaus; Wolber, Gerhard.

Mol Inform ; 40(9): e2100031, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34378348

17.

Live attenuated virus vaccine protects against SARS-CoV-2 variants of concern B.1.1.7 (Alpha) and B.1.351 (Beta).

Trimpert, Jakob; Adler, Julia M; Eschke, Kathrin; Abdelgawad, Azza; Firsching, Theresa C; Ebert, Nadine; Thao, Tran Thi Nhu; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan.

Sci Adv ; 7(49): eabk0172, 2021 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-34851677

18.

Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding.

Trimpert, Jakob; Dietert, Kristina; Firsching, Theresa C; Ebert, Nadine; Thi Nhu Thao, Tran; Vladimirova, Daria; Kaufer, Susanne; Labroussaa, Fabien; Abdelgawad, Azza; Conradie, Andelé; Höfler, Thomas; Adler, Julia M; Bertzbach, Luca D; Jores, Joerg; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan.

Cell Rep ; 36(5): 109493, 2021 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-34320400

19.

Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters.

Osterrieder, Nikolaus; Bertzbach, Luca D; Dietert, Kristina; Abdelgawad, Azza; Vladimirova, Daria; Kunec, Dusan; Hoffmann, Donata; Beer, Martin; Gruber, Achim D; Trimpert, Jakob.

Viruses ; 12(7)2020 07 20.

Artigo em Inglês | MEDLINE | ID: mdl-32698441

20.

The Roborovski Dwarf Hamster Is A Highly Susceptible Model for a Rapid and Fatal Course of SARS-CoV-2 Infection.

Trimpert, Jakob; Vladimirova, Daria; Dietert, Kristina; Abdelgawad, Azza; Kunec, Dusan; Dökel, Simon; Voss, Anne; Gruber, Achim D; Bertzbach, Luca D; Osterrieder, Nikolaus.

Cell Rep ; 33(10): 108488, 2020 12 08.

Artigo em Inglês | MEDLINE | ID: mdl-33271063

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