Detalhe da pesquisa
1.
Inferring secretory and metabolic pathway activity from omic data with secCellFie.
Metab Eng
; 81: 273-285, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38145748
2.
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.
Metab Eng
; 72: 171-187, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35301123
3.
Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells.
Biotechnol Bioeng
; 119(3): 963-982, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34953085
4.
A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis.
J Allergy Clin Immunol
; 148(2): 486-494, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33556465
5.
An enhanced CRISPR repressor for targeted mammalian gene regulation.
Nat Methods
; 15(8): 611-616, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30013045
6.
Systems glycobiology for discovering drug targets, biomarkers, and rational designs for glyco-immunotherapy.
J Biomed Sci
; 28(1): 50, 2021 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34158025
7.
In situ detection of protein interactions for recombinant therapeutic enzymes.
Biotechnol Bioeng
; 118(2): 890-904, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33169829
8.
Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.
Nat Methods
; 14(6): 573-576, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28319113
9.
Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions.
PLoS Comput Biol
; 15(4): e1006867, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30986217
10.
Inferring secretory and metabolic pathway activity from omic data with secCellFie.
bioRxiv
; 2023 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205389
11.
A Novel Tissue-Free Method to Estimate Tumor-Derived Cell-Free DNA Quantity Using Tumor Methylation Patterns.
Cancers (Basel)
; 16(1)2023 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38201510
12.
Dysregulation of the secretory pathway connects Alzheimer's disease genetics to aggregate formation.
Cell Syst
; 12(9): 873-884.e4, 2021 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34171228
13.
From omics to Cellular mechanisms in mammalian cell factory development.
Curr Opin Chem Eng
; 322021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37475722
14.
Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter.
Curr Res Biotechnol
; 1: 49-57, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32577618
15.
Combating viral contaminants in CHO cells by engineering innate immunity.
Sci Rep
; 9(1): 8827, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31222165
16.
The emerging role of systems biology for engineering protein production in CHO cells.
Curr Opin Biotechnol
; 51: 64-69, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29223005
17.
Modulating carbohydrate-protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology.
Curr Opin Struct Biol
; 40: 104-111, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27639240