Detalhe da pesquisa
1.
Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Cell
; 173(2): 430-442.e17, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29606353
2.
BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.
Genes Dev
; 32(23-24): 1537-1549, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30463901
3.
Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.
Genes Dev
; 31(16): 1704-1713, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28916711
4.
Epigenetic inactivation of ERF reactivates γ-globin expression in ß-thalassemia.
Am J Hum Genet
; 108(4): 709-721, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33735615
5.
HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation.
Blood
; 139(21): 3181-3193, 2022 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35040907
6.
Irradiation is not sufficient to eradicate residual immortalized erythroid cells in in vitro-generated red blood cell products.
Transfusion
; 63(6): 1122-1128, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37154531
7.
Recombinant Cas9 protein production in an endotoxin-free system and evaluation with editing the BCL11A gene in human cells.
Protein Expr Purif
; 210: 106313, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37276914
8.
DSLK and Kg: Antithetical antigens in the RHAG blood group system, and characterization of anti-DSLK antibody.
Vox Sang
; 118(5): 392-397, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36908196
9.
Transcriptional silencing of fetal hemoglobin expression by NonO.
Nucleic Acids Res
; 49(17): 9711-9723, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34379783
10.
[In vitro production of red blood cells for future transfusion medicine].
Rinsho Ketsueki
; 64(6): 482-488, 2023.
Artigo
em Japonês
| MEDLINE | ID: mdl-37407471
11.
Lentiviral vector ALS20 yields high hemoglobin levels with low genomic integrations for treatment of beta-globinopathies.
Mol Ther
; 29(4): 1625-1638, 2021 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515514
12.
CRISPR Editing Enables Consequential Tag-Activated MicroRNA-Mediated Endogene Deactivation.
Int J Mol Sci
; 23(3)2022 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163006
13.
GATA zinc finger domain-containing protein 2A (GATAD2A) deficiency reactivates fetal haemoglobin in patients with ß-thalassaemia through impaired formation of methyl-binding domain protein 2 (MBD2)-containing nucleosome remodelling and deacetylation (NuRD) complex.
Br J Haematol
; 193(6): 1220-1227, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33997955
14.
Induction of therapeutic levels of HbF in genome-edited primary ß0 39-thalassaemia haematopoietic stem and progenitor cells.
Br J Haematol
; 192(2): 395-404, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33216968
15.
Long noncoding RNA HBBP1 enhances γ-globin expression through the ETS transcription factor ELK1.
Biochem Biophys Res Commun
; 552: 157-163, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33744764
16.
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site.
Blood
; 133(8): 852-856, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30617196
17.
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Nature
; 527(7577): 192-7, 2015 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26375006
18.
Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells.
Mol Ther
; 28(1): 129-141, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31677955
19.
Distinct miRNA Signatures and Networks Discern Fetal from Adult Erythroid Differentiation and Primary from Immortalized Erythroid Cells.
Int J Mol Sci
; 22(7)2021 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33807258
20.
Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human ß-globin locus.
Blood
; 131(17): 1960-1973, 2018 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29519807