Detalhe da pesquisa
1.
CSF p-tau205: a biomarker of tau pathology in Alzheimer's disease.
Acta Neuropathol
; 147(1): 12, 2024 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184490
2.
Novel ultrasensitive immunoassay for the selective quantification of tau oligomers and related soluble aggregates.
Alzheimers Dement
; 20(4): 2894-2905, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38520322
3.
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease.
Alzheimers Dement
; 20(2): 1239-1249, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37975513
4.
Association of plasma biomarkers with cognition, cognitive decline, and daily function across and within neurodegenerative diseases: Results from the Ontario Neurodegenerative Disease Research Initiative.
Alzheimers Dement
; 20(3): 1753-1770, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38105605
5.
Neurogranin in Alzheimer's disease and ageing: A human post-mortem study.
Neurobiol Dis
; 177: 105991, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36623608
6.
Analytical and clinical validation of a blood progranulin ELISA in frontotemporal dementias.
Clin Chem Lab Med
; 61(12): 2195-2204, 2023 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37476993
7.
γ-Secretase modulators show selectivity for γ-secretase-mediated amyloid precursor protein intramembrane processing.
J Cell Mol Med
; 26(3): 880-892, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931449
8.
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer's Disease Neuroimaging Initiative.
Mol Psychiatry
; 26(2): 429-442, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106600
9.
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Mol Psychiatry
; 26(10): 5766-5788, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647257
10.
Untangling the association of amyloid-ß and tau with synaptic and axonal loss in Alzheimer's disease.
Brain
; 144(1): 310-324, 2021 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33279949
11.
Amyloid pathology and synaptic loss in pathological aging.
J Neurochem
; 159(2): 258-272, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34473357
12.
Molecular forms of neurogranin in cerebrospinal fluid.
J Neurochem
; 157(3): 816-833, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33249594
13.
Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology.
Brain
; 143(2): 650-660, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31834365
14.
Cerebrospinal fluid neurogranin in an inducible mouse model of neurodegeneration: A translatable marker of synaptic degeneration.
Neurobiol Dis
; 134: 104645, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31669672
15.
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease.
Acta Neuropathol
; 137(1): 89-102, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30244311
16.
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology.
Acta Neuropathol
; 136(3): 363-376, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29700597
17.
Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Mol Psychiatry
; 26(10): 5789, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34272490
18.
Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease.
Alzheimers Dement
; 11(10): 1180-90, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533203
19.
Association of region-specific hippocampal reduction of neurogranin with inflammasome proteins in post mortem brains of Alzheimer's disease.
Alzheimers Dement (N Y)
; 10(1): e12444, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38356472
20.
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease neuropathology.
Nat Commun
; 15(1): 2615, 2024 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38521766