Detalhe da pesquisa
1.
HIV-1 cell-to-cell spread overcomes the virus entry block of non-macrophage-tropic strains in macrophages.
PLoS Pathog
; 18(5): e1010335, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35622876
2.
Protein overexpression can induce the elongation of cell membrane nanodomains.
Biophys J
; 122(11): 2112-2124, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36482718
3.
Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis.
PLoS Pathog
; 17(4): e1009526, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33872329
4.
Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands.
Molecules
; 28(3)2023 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36770826
5.
CCR5 structural plasticity shapes HIV-1 phenotypic properties.
PLoS Pathog
; 14(12): e1007432, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30521629
6.
Buffering deleterious polymorphisms in highly constrained parts of HIV-1 envelope by flexible regions.
Retrovirology
; 13(1): 50, 2016 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27473399
7.
HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines.
Proc Natl Acad Sci U S A
; 110(23): 9475-80, 2013 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23696662
8.
Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry.
J Biol Chem
; 289(27): 19042-52, 2014 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24855645
9.
A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity.
Retrovirology
; 12: 50, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26081316
10.
CCR5 mutations distinguish N-terminal modifications of RANTES (CCL5) with agonist versus antagonist activity.
J Virol
; 86(18): 10218-20, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787219
11.
Modeling the allosteric modulation of CCR5 function by Maraviroc.
Drug Discov Today Technol
; 10(2): e297-305, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24050281
12.
Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection.
Sci Adv
; 9(27): eadf8251, 2023 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37406129
13.
Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells.
J Cell Biol
; 222(5)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36988579
14.
Allosteric model of maraviroc binding to CC chemokine receptor 5 (CCR5).
J Biol Chem
; 286(38): 33409-21, 2011 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21775441
15.
New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection.
J Biol Chem
; 286(7): 4978-90, 2011 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21118814
16.
Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status.
Elife
; 112022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35866628
17.
Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling.
J Clin Invest
; 118(3): 1074-84, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18274673
18.
CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.
Blood
; 113(24): 6085-93, 2009 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19380869
19.
Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor.
Viruses
; 13(7)2021 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34372601
20.
CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome.
Blood
; 112(1): 34-44, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18436740