Detalhe da pesquisa
1.
Depressive Symptoms and Plasma Markers of Alzheimer's Disease and Neurodegeneration: A Coordinated Meta-Analysis of 8 Cohort Studies.
Am J Geriatr Psychiatry
; 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38553327
2.
Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis.
Rheumatology (Oxford)
; 62(4): 1669-1676, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040165
3.
Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes.
Rheumatology (Oxford)
; 62(1): 457-466, 2022 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35383365
4.
Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis.
Rheumatology (Oxford)
; 61(7): 3023-3032, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34730803
5.
Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration.
Rheumatology (Oxford)
; 60(3): 1166-1175, 2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32885253
6.
A data-driven methodology reveals novel myofiber clusters in older human muscles.
FASEB J
; 34(4): 5525-5537, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32141137
7.
RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.
Ann Rheum Dis
; 78(2): 270-277, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30504444
8.
The effect of forced exercise on knee joints in Dio2(-/-) mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress.
Ann Rheum Dis
; 75(3): 571-7, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25550340
9.
Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis.
Ann Rheum Dis
; 74(8): 1571-9, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24695009
10.
Genes expressed in blood link osteoarthritis with apoptotic pathways.
Ann Rheum Dis
; 73(10): 1844-53, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23864235
11.
Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2.
Blood
; 127(11): 1512-5, 2016 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26825711
12.
Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity.
Proc Natl Acad Sci U S A
; 107(42): 18046-9, 2010 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20921414
13.
Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations.
Hum Mol Genet
; 18(8): 1518-23, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19181678
14.
Interleukin-1 gene cluster variants with innate cytokine production profiles and osteoarthritis in subjects from the Genetics, Osteoarthritis and Progression Study.
Arthritis Rheum
; 62(4): 1119-26, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20131253
15.
Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility-Towards Identification of Applicable Early OA Biomarkers.
Biomolecules
; 11(9)2021 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34572569
16.
Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis.
Rheumatol Ther
; 8(1): 499-515, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33608843
17.
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.
Arthritis Rheumatol
; 73(5): 789-799, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33258547
18.
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis.
Hum Mol Genet
; 17(12): 1867-75, 2008 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18334578
19.
Elucidating Epigenetic Regulation by Identifying Functional cis-Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage.
Arthritis Rheumatol
; 72(11): 1845-1854, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32840049
20.
Annotating Transcriptional Effects of Genetic Variants in Disease-Relevant Tissue: Transcriptome-Wide Allelic Imbalance in Osteoarthritic Cartilage.
Arthritis Rheumatol
; 71(4): 561-570, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30298554