Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB.

Lampson, Benjamin L; RamÎ¯rez, Ana S; Baro, Marta; He, Lixia; Hegde, Mudra; Koduri, Vidyasagar; Pfaff, Jamie L; Hanna, Ruth E; Kowal, Julia; Shirole, Nitin H; He, Yanfeng; Doench, John G; Contessa, Joseph N; Locher, Kaspar P; Kaelin, William G.

Cell ; 187(9): 2209-2223.e16, 2024 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-38670073

2.

Acalabrutinib, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia: a single-arm, open-label, phase 2 study.

Davids, Matthew S; Lampson, Benjamin L; Tyekucheva, Svitlana; Wang, Zixu; Lowney, Jessica C; Pazienza, Samantha; Montegaard, Josie; Patterson, Victoria; Weinstock, Matthew; Crombie, Jennifer L; Ng, Samuel Y; Kim, Austin I; Jacobson, Caron A; LaCasce, Ann S; Armand, Philippe; Arnason, Jon E; Fisher, David C; Brown, Jennifer R.

Lancet Oncol ; 22(10): 1391-1402, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34534514

3.

Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity.

Lampson, Benjamin L; Kasar, Siddha N; Matos, Tiago R; Morgan, Elizabeth A; Rassenti, Laura; Davids, Matthew S; Fisher, David C; Freedman, Arnold S; Jacobson, Caron A; Armand, Philippe; Abramson, Jeremy S; Arnason, Jon E; Kipps, Thomas J; Fein, Joshua; Fernandes, Stacey; Hanna, John; Ritz, Jerome; Kim, Haesook T; Brown, Jennifer R.

Blood ; 128(2): 195-203, 2016 07 14.

Artigo em Inglês | MEDLINE | ID: mdl-27247136

4.

Activity of erlotinib when dosed below the maximum tolerated dose for EGFR-mutant lung cancer: Implications for targeted therapy development.

Lampson, Benjamin L; Nishino, Mizuki; Dahlberg, Suzanne E; Paul, Danie; Santos, Abigail A; Jänne, Pasi A; Oxnard, Geoffrey R.

Cancer ; 122(22): 3456-3463, 2016 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-27525836

5.

A new triple threat to CLL.

Lampson, Benjamin L; Davids, Matthew S.

Blood ; 132(15): 1547-1548, 2018 10 11.

Artigo em Inglês | MEDLINE | ID: mdl-30309874

6.

CLINICAL PROBLEM-SOLVING. Tip of the Tongue.

Lampson, Benjamin L; Gray, Stacy W; Cibas, Edmund S; Levy, Bruce D; Loscalzo, Joseph.

N Engl J Med ; 375(9): 880-6, 2016 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-27579639

7.

Ventricular arrhythmias and sudden death in patients taking ibrutinib.

Lampson, Benjamin L; Yu, Lijian; Glynn, Robert J; Barrientos, Jacqueline C; Jacobsen, Eric D; Banerji, Versha; Jones, Jeffrey A; Walewska, Renata; Savage, Kerry J; Michaud, Gregory F; Moslehi, Javid J; Brown, Jennifer R.

Blood ; 129(18): 2581-2584, 2017 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-28223277

8.

Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia.

Lampson, Benjamin L; Gupta, Aditi; Tyekucheva, Svitlana; Mashima, Kiyomi; Petrácková, Anna; Wang, Zixu; Wojciechowska, Natalia; Shaughnessy, Conner J; Baker, Peter O; Fernandes, Stacey M; Shupe, Samantha; Machado, John-Hanson; Fardoun, Rayan; Kim, Annette S; Brown, Jennifer R.

J Clin Oncol ; 41(5): 1116-1128, 2023 02 10.

Artigo em Inglês | MEDLINE | ID: mdl-36315919

9.

The Evolving Use of Phosphatidylinositol 3-Kinase Inhibitors for the Treatment of Chronic Lymphocytic Leukemia.

Lampson, Benjamin L; Brown, Jennifer R.

Hematol Oncol Clin North Am ; 35(4): 807-826, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34174987

10.

Targeting oncoproteins with a positive selection assay for protein degraders.

Koduri, Vidyasagar; Duplaquet, Leslie; Lampson, Benjamin L; Wang, Adam C; Sabet, Amin H; Ishoey, Mette; Paulk, Joshiawa; Teng, Mingxing; Harris, Isaac S; Endress, Jennifer E; Liu, Xiaoxi; Dasilva, Ethan; Paulo, Joao A; Briggs, Kimberly J; Doench, John G; Ott, Christopher J; Zhang, Tinghu; Donovan, Katherine A; Fischer, Eric S; Gygi, Steven P; Gray, Nathanael S; Bradner, James; Medin, Jeffrey A; Buhrlage, Sara J; Oser, Matthew G; Kaelin, William G.

Sci Adv ; 7(6)2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33547076

11.

Efficacy results of a phase 2 trial of first-line idelalisib plus ofatumumab in chronic lymphocytic leukemia.

Lampson, Benjamin L; Kim, Haesook T; Davids, Matthew S; Abramson, Jeremy S; Freedman, Arnold S; Jacobson, Caron A; Armand, Philippe A; Joyce, Robin M; Arnason, Jon E; Rassenti, Laura Z; Kipps, Thomas J; Fein, Joshua; Fernandes, Stacey M; Hanna, John R; Fisher, David C; Brown, Jennifer R.

Blood Adv ; 3(7): 1167-1174, 2019 04 09.

Artigo em Inglês | MEDLINE | ID: mdl-30967392

12.

Are BTK and PLCG2 mutations necessary and sufficient for ibrutinib resistance in chronic lymphocytic leukemia?

Lampson, Benjamin L; Brown, Jennifer R.

Expert Rev Hematol ; 11(3): 185-194, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29381098

13.

PI3KÎ´-selective and PI3Kα/Î´-combinatorial inhibitors in clinical development for B-cell non-Hodgkin lymphoma.

Lampson, Benjamin L; Brown, Jennifer R.

Expert Opin Investig Drugs ; 26(11): 1267-1279, 2017 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-28945111

14.

The Development and Current Use of BCL-2 Inhibitors for the Treatment of Chronic Lymphocytic Leukemia.

Lampson, Benjamin L; Davids, Matthew S.

Curr Hematol Malig Rep ; 12(1): 11-19, 2017 02.

Artigo em Inglês | MEDLINE | ID: mdl-28116634

15.

High-grade heart block associated with ibrutinib therapy.

Vartanov, Alexander R; Lampson, Benjamin L; Jacobsen, Eric D; Alyea, Edwin P; Moslehi, Javid J; Brown, Jennifer R.

HeartRhythm Case Rep ; 7(6): 391-394, 2021 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-34194987

16.

Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.

Weyandt, Jamie D; Lampson, Benjamin L; Tang, Sherry; Mastrodomenico, Matthew; Cardona, Diana M; Counter, Christopher M.

PLoS One ; 10(10): e0140253, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26452271

17.

Rare codons capacitate Kras-driven de novo tumorigenesis.

Pershing, Nicole L K; Lampson, Benjamin L; Belsky, Jason A; Kaltenbrun, Erin; MacAlpine, David M; Counter, Christopher M.

J Clin Invest ; 125(1): 222-33, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25437878

18.

For CLL cells, there's no place like home.

Lampson, Benjamin L; Brown, Jennifer R.

Leuk Lymphoma ; 60(14): 3347-3349, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31373247

19.

Rare codons regulate KRas oncogenesis.

Lampson, Benjamin L; Pershing, Nicole L K; Prinz, Joseph A; Lacsina, Joshua R; Marzluff, William F; Nicchitta, Christopher V; MacAlpine, David M; Counter, Christopher M.

Curr Biol ; 23(1): 70-5, 2013 Jan 07.

Artigo em Inglês | MEDLINE | ID: mdl-23246410

20.

Targeting eNOS in pancreatic cancer.

Lampson, Benjamin L; Kendall, S Disean; Ancrile, Brooke B; Morrison, Meghan M; Shealy, Michael J; Barrientos, Katharine S; Crowe, Matthew S; Kashatus, David F; White, Rebekah R; Gurley, Susan B; Cardona, Diana M; Counter, Christopher M.

Cancer Res ; 72(17): 4472-82, 2012 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-22738914

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Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB.

Acalabrutinib, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia: a single-arm, open-label, phase 2 study.

Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity.

Activity of erlotinib when dosed below the maximum tolerated dose for EGFR-mutant lung cancer: Implications for targeted therapy development.

A new triple threat to CLL.

CLINICAL PROBLEM-SOLVING. Tip of the Tongue.

Ventricular arrhythmias and sudden death in patients taking ibrutinib.

Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia.

The Evolving Use of Phosphatidylinositol 3-Kinase Inhibitors for the Treatment of Chronic Lymphocytic Leukemia.

Targeting oncoproteins with a positive selection assay for protein degraders.

Efficacy results of a phase 2 trial of first-line idelalisib plus ofatumumab in chronic lymphocytic leukemia.

Are BTK and PLCG2 mutations necessary and sufficient for ibrutinib resistance in chronic lymphocytic leukemia?

PI3KÎ´-selective and PI3Kα/Î´-combinatorial inhibitors in clinical development for B-cell non-Hodgkin lymphoma.

The Development and Current Use of BCL-2 Inhibitors for the Treatment of Chronic Lymphocytic Leukemia.

High-grade heart block associated with ibrutinib therapy.

Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.

Rare codons capacitate Kras-driven de novo tumorigenesis.

For CLL cells, there's no place like home.

Rare codons regulate KRas oncogenesis.

Targeting eNOS in pancreatic cancer.