Detalhe da pesquisa
1.
Identification of novel Aß-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease.
Mol Cell Neurosci
; 114: 103630, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34029694
2.
3, 9-di-O-substituted coumestrols incorporating basic amine side chains act as novel apoptosis inducers with improved pharmacological selectivity.
Bioorg Chem
; 85: 140-151, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30612080
3.
Design, synthesis, and biological evaluation of novel androst-17ß-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists.
J Enzyme Inhib Med Chem
; 34(1): 1597-1606, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31469015
4.
Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17ß-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists.
Bioorg Med Chem Lett
; 27(17): 4212-4217, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757062
5.
Synthesis and biological evaluation of 2,3-diaryl isoquinolinone derivatives as anti-breast cancer agents targeting ERα and VEGFR-2.
Bioorg Med Chem Lett
; 24(9): 2129-33, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24721727
6.
Discovery of novel aromatase inhibitors using a homogeneous time-resolved fluorescence assay.
Acta Pharmacol Sin
; 35(8): 1082-92, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25047514
7.
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer's Disease: Long Road Ahead.
Curr Drug Targets
; 23(11): 1040-1056, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35593357
8.
Rapid and highly specific detection of site-specific 5-hydroxymethylcytosine based on peroxotungstate oxidation and mismatch ligation-based LAMP.
RSC Adv
; 12(31): 19885-19889, 2022 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35865199
9.
Therapeutic Strategies Targeting Amyloid-ß Receptors and Transporters in Alzheimer's Disease.
J Alzheimers Dis
; 79(4): 1429-1442, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33459712
10.
(m)RVD-hemopressin (α) and (m)VD-hemopressin (α) improve the memory-impairing effect of scopolamine in novel object and object location recognition tasks in mice.
Peptides
; 136: 170442, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33171279
11.
AMPK alleviates oxidative stressinduced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop.
Mech Ageing Dev
; 191: 111347, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32882228
12.
Effect of (m)VD-hemopressin against Aß1-42-induced oxidative stress and apoptosis in mouse hippocampal neurons.
Peptides
; 124: 170185, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31730791
13.
Drug development for Alzheimer's disease: review.
J Drug Target
; 27(2): 164-173, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29732929
14.
Design and synthesis of novel steroidal imidazoles as dual inhibitors of AR/CYP17 for the treatment of prostate cancer.
Steroids
; 150: 108384, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30885648
15.
Potential Astrocytic Receptors and Transporters in the Pathogenesis of Alzheimer's Disease.
J Alzheimers Dis
; 67(4): 1109-1122, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30741675
16.
Aerobic exercise promotes the expression of ERCC1 to prolong lifespan: A new possible mechanism.
Med Hypotheses
; 122: 22-25, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30593415
17.
Stability and inhibitory function of Treg cells under inflammatory conditions in vitro.
Exp Ther Med
; 18(4): 2443-2450, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31555356
18.
Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity.
Eur J Med Chem
; 150: 783-795, 2018 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29587221
19.
Aerobic exercise-stimulated Klotho upregulation extends life span by attenuating the excess production of reactive oxygen species in the brain and kidney.
Exp Ther Med
; 16(4): 3511-3517, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30233703
20.
Gpn2 and Rba50 Directly Participate in the Assembly of the Rpb3 Subcomplex in the Biogenesis of RNA Polymerase II.
Mol Cell Biol
; 38(13)2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29661922