Detalhe da pesquisa
1.
In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor.
Antimicrob Agents Chemother
; 66(12): e0092122, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36448795
2.
Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes.
J Lipid Res
; 61(6): 870-883, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32156718
3.
The sialic acid transporter NanT is necessary and sufficient for uptake of 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) and its azido analog in Escherichia coli.
Mol Microbiol
; 110(2): 204-218, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30076772
4.
Two-Step Azidoalkenylation of Terminal Alkenes Using Iodomethyl Sulfones.
Molecules
; 24(22)2019 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31752245
5.
Molecular characterization and verification of azido-3,8-dideoxy-d-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide.
J Biol Chem
; 292(48): 19840-19848, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018092
6.
MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery.
J Med Chem
; 67(3): 2118-2128, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38270627
7.
Ligandability Assessment of IL-1ß by Integrated Hit Identification Approaches.
J Med Chem
; 67(10): 8141-8160, 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38728572
8.
Concise synthesis of pyrrolidine and indolizidine alkaloids by a highly convergent three-component reaction.
Chemistry
; 17(11): 3207-12, 2011 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21308816
9.
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.
J Med Chem
; 64(9): 6329-6357, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33929852
10.
Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
J Med Chem
; 63(14): 7773-7816, 2020 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32634310
11.
Concise total syntheses of (-)-jorunnamycin A and (-)-jorumycin enabled by asymmetric catalysis.
Science
; 363(6424): 270-275, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573544
12.
Correction to "MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery".
J Med Chem
; 67(6): 5111-5112, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471144
13.
Synthesis of polysubstituted N-H pyrroles from vinyl azides and 1,3-dicarbonyl compounds.
Org Lett
; 10(2): 313-6, 2008 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-18154344
14.
4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors.
Bioorg Med Chem Lett
; 18(4): 1502-6, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18207391
15.
Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline.
J Med Chem
; 61(20): 9360-9370, 2018 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30226381
16.
Nucleophilic 5-endo-trig cyclizations of N-homoallylic sulfonamides: a facile method for the construction of pyrrolidine rings.
Chem Commun (Camb)
; (26): 2698-700, 2007 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17594024
17.
Synthesis of Aryl Ketoamides via Aryne Insertion into Imides.
Org Lett
; 18(12): 2793-5, 2016 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27266278
18.
Total synthesis of (±)-cylindricine C.
Org Lett
; 13(18): 4774-7, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21838228