Detalhe da pesquisa
1.
KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma.
J Neurooncol
; 140(3): 519-527, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30238350
2.
Assessment of reliability and validity of a handheld surface spine scanner for measuring trunk rotation in adolescent idiopathic scoliosis.
Spine Deform
; 11(6): 1347-1354, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37493936
3.
Phase 1 clinical trial to assess safety and efficacy of NY-ESO-1-specific TCR T cells in HLA-A∗02:01 patients with advanced soft tissue sarcoma.
Cell Rep Med
; 4(8): 101133, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37586317
4.
Automated System for Multiplexing Detection of COVID-19 and Other Respiratory Pathogens.
IEEE J Transl Eng Health Med
; 11: 424-434, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37435542
5.
Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations.
J Med Chem
; 65(1): 191-216, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34928144
6.
Jinhua Qinggan granules for non-hospitalized COVID-19 patients: A double-blind, placebo-controlled, and randomized controlled trial.
Front Med (Lausanne)
; 9: 928468, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35979216
7.
Hepatic expression of cell proliferation markers and growth factors in giant cell hepatitis: implications for the pathogenetic mechanisms involved.
J Pediatr Gastroenterol Nutr
; 52(1): 65-72, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21119537
8.
Discovery of Encequidar, First-in-Class Intestine Specific P-glycoprotein Inhibitor.
J Med Chem
; 64(7): 3677-3693, 2021 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33729781
9.
Apolipoprotein E Gene Revisited: Contribution of Rare Variants to Alzheimer's Disease Susceptibility in Southern Chinese.
Curr Alzheimer Res
; 18(1): 67-79, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761857
10.
Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.
Eur J Med Chem
; 191: 112118, 2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32113126
11.
Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361).
J Med Chem
; 61(11): 4704-4719, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29617135
12.
Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.
Sci Rep
; 8(1): 1853, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29382849
13.
RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg.
Sci Transl Med
; 9(409)2017 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28954926
14.
Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection: An Open-label Randomized, Controlled, Phase IIb/III Trial.
Chest
; 151(5): 1069-1080, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27884765
15.
Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial.
Lancet Infect Dis
; 16(2): 209-18, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26559482
16.
MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2.
Nat Microbiol
; 1: 16004, 2016 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27572168
17.
Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities.
Antiviral Res
; 121: 47-58, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26092643
18.
Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent.
Antiviral Res
; 121: 97-108, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26129970
19.
Hepatitis C virus therapies: current treatments, targets and future perspectives.
Antivir Chem Chemother
; 14(1): 1-21, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12790512
20.
Specific, sensitive and accurate liquid chromatographic-tandem mass spectrometric method for the measurement of ribavirin in rat and monkey plasma.
J Chromatogr B Analyt Technol Biomed Life Sci
; 779(2): 241-8, 2002 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12361738