Detalhe da pesquisa
1.
Discovery and mechanistic study of Imperatorin that inhibits HBsAg expression and cccDNA transcription.
J Med Virol
; 96(5): e29669, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38773784
2.
MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus.
Cardiovasc Diabetol
; 23(1): 96, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38486199
3.
Pomiferin targets SERCA, mTOR, and P-gp to induce autophagic cell death in apoptosis-resistant cancer cells, and reverses the MDR phenotype in cisplatin-resistant tumors in vivo.
Pharmacol Res
; 191: 106769, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37061145
4.
Tricin promoted ATG-7 dependent autophagic degradation of α-synuclein and dopamine release for improving cognitive and motor deficits in Parkinson's disease.
Pharmacol Res
; 196: 106874, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37586619
5.
Mutant p53R211* ameliorates inflammatory arthritis in AIA rats via inhibition of TBK1-IRF3 innate immune response.
Inflamm Res
; 72(12): 2199-2219, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37935918
6.
Lipotoxicity-induced mtDNA release promotes diabetic cardiomyopathy by activating the cGAS-STING pathway in obesity-related diabetes.
Cell Biol Toxicol
; 39(1): 277-299, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235096
7.
Ameliorative effect of Luffa cylindrica fruits on Caenorhabditis elegans and cellular models of Alzheimer's disease-related pathology via autophagy induction.
Phytother Res
; 37(10): 4639-4654, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37394882
8.
Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19.
Clin Immunol
; 244: 109093, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944881
9.
Atomic zinc sites with hierarchical porous carbon for high-throughput chemical screening with high loading capacity and stability.
Pharmacol Res
; 178: 106154, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35248698
10.
Ursolic acid enhances the antitumor effects of sorafenib associated with Mcl-1-related apoptosis and SLC7A11-dependent ferroptosis in human cancer.
Pharmacol Res
; 182: 106306, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35714823
11.
Traditional Patchouli essential oil modulates the host's immune responses and gut microbiota and exhibits potent anti-cancer effects in ApcMin /+ mice.
Pharmacol Res
; 176: 106082, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35032662
12.
The role of non-coding RNAs (miRNA and lncRNA) in the clinical management of rheumatoid arthritis.
Pharmacol Res
; 186: 106549, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36368452
13.
SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome.
Clin Sci (Lond)
; 135(12): 1505-1522, 2021 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34128977
14.
Non-Digestible Carbohydrate and the Risk of Colorectal Neoplasia: A Systematic Review.
Nutr Cancer
; 73(1): 31-44, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202158
15.
Potential therapeutic compounds from traditional Chinese medicine targeting endoplasmic reticulum stress to alleviate rheumatoid arthritis.
Pharmacol Res
; 170: 105696, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34052360
16.
Icariin enhances youth-like features by attenuating the declined gut microbiota in the aged mice.
Pharmacol Res
; 168: 105587, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33798737
17.
Saponins isolated from Radix polygalae extent lifespan by modulating complement C3 and gut microbiota.
Pharmacol Res
; 170: 105697, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34062240
18.
Lychee seed polyphenol protects the blood-brain barrier through inhibiting Aß(25-35)-induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1-mediated autophagy in bEnd.3 cells and APP/PS1 mice.
Phytother Res
; 35(2): 954-973, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32893437
19.
A Functional Variant in Ubiquitin Conjugating Enzyme E2 L3 Contributes to Hepatitis B Virus Infection and Maintains Covalently Closed Circular DNA Stability by Inducing Degradation of Apolipoprotein B mRNA Editing Enzyme Catalytic Subunit 3A.
Hepatology
; 69(5): 1885-1902, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30614547
20.
SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.
Pharmacol Res
; 153: 104660, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31982489