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Foodborne Pathog Dis ; 21(8): 485-490, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38700849

RESUMO

The degree of contamination of retail meat with colistin-resistant bacteria and its potential contribution to dissemination within communities remains to be determined. Thus, we aimed to elucidate the contamination status of colistin-resistance genes, indicative of colistin-resistant bacteria, in retail meats in Vietnam. In total, 46 chicken and 49 pork meats from stores in Vietnam and Japan were examined. Multiplex real-time polymerase chain reaction with TaqMan probes was performed for detecting mcr-1, mcr-3, and Escherichia coli 16S rRNA. Colistin-resistant bacteria in meats were isolated using selective media. The minimum inhibitory concentrations of colistin were determined using the broth microdilution method. The results showed that 70.7% of chicken meats in Vietnam were contaminated with both mcr-1 and mcr-3. Meanwhile, mcr-1 and mcr-3 were detected in 15.9% and 40.9% of pork meat, respectively. Only mcr-3 was detected in 40% of chicken in Japan. In addition, mcr-1-harboring E. coli and mcr-3-harboring Aeromonas were isolated from chicken meats in Vietnam. Some of these isolates showed colistin resistance. These results showed that most retail meats were highly contaminated with colistin-resistance genes. Notably, our results suggest that mcr-3 is more prevalent in the contaminated samples compared with mcr-1.


Assuntos
Antibacterianos , Galinhas , Colistina , Farmacorresistência Bacteriana , Proteínas de Escherichia coli , Escherichia coli , Microbiologia de Alimentos , Carne , Testes de Sensibilidade Microbiana , Vietnã , Colistina/farmacologia , Animais , Galinhas/microbiologia , Farmacorresistência Bacteriana/genética , Antibacterianos/farmacologia , Proteínas de Escherichia coli/genética , Escherichia coli/efeitos dos fármacos , Escherichia coli/isolamento & purificação , Escherichia coli/genética , Carne/microbiologia , Suínos , RNA Ribossômico 16S/genética , Japão , Contaminação de Alimentos/análise , Carne de Porco/microbiologia , Transferases (Outros Grupos de Fosfato Substituídos)
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