Detalhe da pesquisa
1.
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Nature
; 629(8013): 919-926, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38589574
2.
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Nature
; 629(8013): 927-936, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588697
3.
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Nat Chem Biol
; 17(10): 1065-1074, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168367
4.
Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Nat Chem Biol
; 17(8): 925, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34188221
5.
Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Nat Chem Biol
; 17(11): 1209, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616097
6.
Aqueous-Soluble, Acid-Transforming Chitosan for Efficient and Stimuli-Responsive Gene Silencing.
Biomacromolecules
; 19(5): 1508-1516, 2018 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29562124
7.
Thyroid hormone replacement therapy attenuates atrial remodeling and reduces atrial fibrillation inducibility in a rat myocardial infarction-heart failure model.
J Card Fail
; 20(12): 1012-9, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25305503
8.
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.
Cancer Discov
; : OF1-OF24, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593348
9.
Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML.
Cell Rep Med
; 4(11): 101290, 2023 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992684
10.
Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors.
J Med Chem
; 66(1): 149-169, 2023 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36533617
11.
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
bioRxiv
; 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38105998
12.
Efficacy of a Novel Bi-Steric mTORC1 Inhibitor in Models of B-Cell Acute Lymphoblastic Leukemia.
Front Oncol
; 11: 673213, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34408976
13.
Community acquired Klebsiella pneumoniae meningitis: a case report.
Germs
; 8(2): 92-95, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29951382
14.
Online gaming in the context of social anxiety.
Psychol Addict Behav
; 29(2): 473-82, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25938630
15.
Mechanisms of resistance to EGFR targeted therapies.
Cancer Biol Ther
; 14(4): 304-14, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23358468
16.
Both hypothyroidism and hyperthyroidism increase atrial fibrillation inducibility in rats.
Circ Arrhythm Electrophysiol
; 6(5): 952-9, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24036190
17.
Seeking safety on the internet: relationship between social anxiety and problematic internet use.
J Anxiety Disord
; 26(1): 197-205, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22169053