Detalhe da pesquisa
1.
Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses.
Immunity
; 54(12): 2772-2783.e5, 2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34788602
2.
A Bacterial and Ganglioside-based Nanoparticle Initiates Reprogramming of Macrophages and Promotes Antitumor Phenotypes.
J Immunol
; 212(3): 475-486, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117752
3.
Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing.
Biotechnol Bioeng
; 121(4): 1284-1297, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240126
4.
Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing.
Biotechnol Bioeng
; 121(1): 291-305, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37877536
5.
Comparison of vector elements and process conditions in transient and stable suspension HEK293 platforms using SARS-CoV-2 receptor binding domain as a model protein.
BMC Biotechnol
; 23(1): 7, 2023 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36882740
6.
High-efficiency and multilocus targeted integration in CHO cells using CRISPR-mediated donor nicking and DNA repair inhibitors.
Biotechnol Bioeng
; 120(9): 2419-2440, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37039773
7.
A compendium of stable hotspots in the CHO genome.
Biotechnol Bioeng
; 120(8): 2133-2143, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37014810
8.
Driving adoption of new technologies in biopharmaceutical manufacturing.
Biotechnol Bioeng
; 120(9): 2765-2770, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37053004
9.
Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing.
Biotechnol Bioeng
; 120(11): 3148-3162, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37475681
10.
Characterization and implications of host-cell protein aggregates in biopharmaceutical processing.
Biotechnol Bioeng
; 120(4): 1068-1080, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36585356
11.
Generation of reference cell lines, media, and a process platform for CHO cell biomanufacturing.
Biotechnol Bioeng
; 120(3): 715-725, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36411514
12.
Plasmacytoid dendritic cells cross-prime naive CD8 T cells by transferring antigen to conventional dendritic cells through exosomes.
Proc Natl Acad Sci U S A
; 117(38): 23730-23741, 2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32879009
13.
VSSP abrogates murine ovarian tumor-associated myeloid cell-driven immune suppression and induces M1 polarization in tumor-associated macrophages from ovarian cancer patients.
Cancer Immunol Immunother
; 71(10): 2355-2369, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35166871
14.
Comprehensive assessment of host cell protein expression after extended culture and bioreactor production of CHO cell lines.
Biotechnol Bioeng
; 119(8): 2221-2238, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508759
15.
Biomanufacturing readiness levels [BRL]-A shared vocabulary for biopharmaceutical technology development and commercialization.
Biotechnol Bioeng
; 119(12): 3526-3536, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36071569
16.
Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells.
Biotechnol Bioeng
; 119(3): 963-982, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34953085
17.
Bioindustrial manufacturing readiness levels (BioMRLs) as a shared framework for measuring and communicating the maturity of bioproduct manufacturing processes.
J Ind Microbiol Biotechnol
; 49(5)2022 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150719
18.
EvalDNA: a machine learning-based tool for the comprehensive evaluation of mammalian genome assembly quality.
BMC Bioinformatics
; 22(1): 570, 2021 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837948
19.
PARC: ultrafast and accurate clustering of phenotypic data of millions of single cells.
Bioinformatics
; 36(9): 2778-2786, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31971583
20.
Systematic identification of safe harbor regions in the CHO genome through a comprehensive epigenome analysis.
Biotechnol Bioeng
; 118(2): 659-675, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33049068