Detalhe da pesquisa
1.
Mapping human haematopoietic stem cells from haemogenic endothelium to birth.
Nature
; 604(7906): 534-540, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35418685
2.
A quantitative systems pharmacology workflow toward optimal design and biomarker stratification of atopic dermatitis clinical trials.
J Allergy Clin Immunol
; 153(5): 1330-1343, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38369029
3.
A stimulus-contingent positive feedback loop enables IFN-ß dose-dependent activation of pro-inflammatory genes.
Mol Syst Biol
; 19(5): e11294, 2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36929731
4.
RelB-deficient autoinflammatory pathology presents as interferonopathy, but in mice is interferon-independent.
J Allergy Clin Immunol
; 152(5): 1261-1272, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37460023
5.
NFκB pathway dysregulation due to reduced RelB expression leads to severe autoimmune disorders and declining immunity.
J Autoimmun
; 137: 102946, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36402602
6.
Identifying the combinatorial control of signal-dependent transcription factors.
PLoS Comput Biol
; 17(6): e1009095, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34166361
7.
Stratification of asthma phenotypes by airway proteomic signatures.
J Allergy Clin Immunol
; 144(1): 70-82, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30928653
8.
Identification and prospective stability of electronic nose (eNose)-derived inflammatory phenotypes in patients with severe asthma.
J Allergy Clin Immunol
; 143(5): 1811-1820.e7, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30529449
9.
Pathway discovery using transcriptomic profiles in adult-onset severe asthma.
J Allergy Clin Immunol
; 141(4): 1280-1290, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28756296
10.
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.
Eur Respir J
; 51(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29650557
11.
A Severe Asthma Disease Signature from Gene Expression Profiling of Peripheral Blood from U-BIOPRED Cohorts.
Am J Respir Crit Care Med
; 195(10): 1311-1320, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27925796
12.
A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED.
Am J Respir Crit Care Med
; 195(4): 443-455, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27580351
13.
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
J Allergy Clin Immunol
; 139(6): 1797-1807, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27773852
14.
Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma.
Eur Respir J
; 50(3)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28954779
15.
Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study.
Eur Respir J
; 48(5): 1307-1319, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799384
16.
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux.
Eur Respir J
; 53(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31023846
17.
Comparing the Efficacy of Two Generations of EGFR-TKIs: An Integrated Drug-Disease Mechanistic Model Approach in EGFR-Mutated Lung Adenocarcinoma.
Biomedicines
; 12(3)2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38540317
18.
Kinetics of mRNA nuclear export regulate innate immune response gene expression.
Nat Commun
; 13(1): 7197, 2022 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36424375
19.
Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort.
Clin Transl Med
; 12(4): e816, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35474304
20.
IκBα is required for full transcriptional induction of some NFκB-regulated genes in response to TNF in MCF-7 cells.
NPJ Syst Biol Appl
; 7(1): 42, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34853340