Detalhe da pesquisa
1.
Precise druggability of the PTH type 1 receptor.
Nat Chem Biol
; 18(3): 272-280, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34949836
2.
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex.
Nature
; 555(7694): 121-125, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29466332
3.
Identification of PXR Activators from Uncaria Rhynchophylla (Gou Teng) and Uncaria Tomentosa (Cat's Claw).
Drug Metab Dispos
; 51(5): 629-636, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36797057
4.
Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction.
Ecotoxicol Environ Saf
; 266: 115605, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37864966
5.
Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation.
Nat Chem Biol
; 16(10): 1096-1104, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32632293
6.
Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity.
Chem Res Toxicol
; 34(12): 2534-2539, 2021 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34788025
7.
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism.
J Biol Chem
; 293(24): 9370-9387, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29717000
8.
Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in ß-arrestin 1/2 signaling.
Eur J Pharmacol
; 968: 176419, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38360293
9.
Activation of PXR causes drug interactions with Paxlovid in transgenic mice.
Acta Pharm Sin B
; 13(11): 4502-4510, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37969744
10.
Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors.
Eur J Med Chem
; 259: 115666, 2023 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37482017
11.
Iron metabolism mediates the relationship between Vitamin C and hepatic steatosis and fibrosis in NAFLD.
Front Nutr
; 9: 952056, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36159474
12.
LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3.
Environ Pollut
; 293: 118542, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34801623
13.
A historic study that opened a new chapter in nutritional science.
Acta Pharmacol Sin
; 37(12): 1641-1644, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27867188
14.
PFOS Inhibited Normal Functional Development of Placenta Cells via PPARγ Signaling.
Biomedicines
; 9(6)2021 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34203907
15.
PPARγ Regulates Triclosan Induced Placental Dysfunction.
Cells
; 11(1)2021 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35011648
16.
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.
Sci Signal
; 14(703): eabc5944, 2021 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34609896
17.
G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells.
Oncotarget
; 7(11): 12823-39, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26871479
18.
Application of chemical biology in target identification and drug discovery.
Arch Pharm Res
; 38(9): 1642-50, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26242900