Detalhe da pesquisa
1.
SIKs Regulate HDAC7 Stabilization and Cytokine Recall in Late-Stage T Cell Effector Differentiation.
J Immunol
; 211(12): 1767-1782, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37947442
2.
Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models.
Cancer Immunol Immunother
; 67(8): 1271-1284, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29923026
3.
Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers.
bioRxiv
; 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292712
4.
Metabolic reprogramming of tumor-associated macrophages using glutamine antagonist JHU083 drives tumor immunity in myeloid-rich prostate and bladder cancer tumors.
Cancer Immunol Res
; 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38701369
5.
Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis.
bioRxiv
; 2023 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865287
6.
Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis.
Nat Commun
; 14(1): 7427, 2023 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37973991
7.
Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy.
J Immunother Cancer
; 10(2)2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135866
8.
Interrogation of T Cell-Enriched Tumors Reveals Prognostic and Immunotherapeutic Implications of Polyamine Metabolism.
Cancer Res Commun
; 2(7): 639-652, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36052016
9.
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug.
Sci Adv
; 8(46): eabq5925, 2022 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383674
10.
Fueling the Revolution: Targeting Metabolism to Enhance Immunotherapy.
Cancer Immunol Res
; 9(3): 255-260, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33648947
11.
Metabolism of immune cells in cancer.
Nat Rev Cancer
; 20(9): 516-531, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32632251
12.
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells.
J Clin Invest
; 130(7): 3865-3884, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32324593
13.
Targeting metabolism to regulate immune responses in autoimmunity and cancer.
Nat Rev Drug Discov
; 18(9): 669-688, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363227
14.
Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Science
; 366(6468): 1013-1021, 2019 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699883
15.
Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation.
J Clin Invest
; 129(11): 4708-4723, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31393856
16.
Targeting adenosine for cancer immunotherapy.
J Immunother Cancer
; 6(1): 57, 2018 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29914571
17.
Something in the air: hyperoxic conditioning of the tumor microenvironment for enhanced immunotherapy.
Cancer Cell
; 27(4): 435-6, 2015 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25873169
18.
A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy.
Comput Struct Biotechnol J
; 13: 265-72, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25941561
19.
Autophagy: a targetable linchpin of cancer cell metabolism.
Trends Endocrinol Metab
; 24(4): 209-17, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23474062